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Extraparenchymal ovarian and testicular Leydig cells: ectopic/heterotopic or orthotopic?
Arch Gynecol Obstet ; 298(3): 655-661, 2018 09.
Artigo em Inglês | MEDLINE | ID: mdl-29971558


We are conducting a prospective study trying to determine, in both sexes, the frequency of appearance of ectopic Leydig cells, their preferred location, their relationship with nerve structures and the possible causes of their appearance.


We have studied 86 cases that were removed according to different clinical indications for pathological study: uterine leyomiomas (n = 12), ovarian cystadenoma (n = 4), endometrial hyperplasia (n = 8), endometrial carcinoma (n = 12), cervical carcinoma (n = 4), seminoma (n = 4), fallopian tube ligatures (n = 24), vasectomies (n = 8), nonspecific orchiepididymitis (n = 2), and unknown (n = 8).


We have observed ectopic Leydig cells in 13/86 cases (15.11%), 9/72 in the female samples (12.50%) and 4/14 in male samples (28.57%). The most frequent location was the mesosalpinx (4 of 13: 30.76%).


These high figures lead us to believe that the ectopia of Leydig cells is not really a pathologic entity, but a finding related to specific functions yet to be determined.





Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Testículo / Células Intersticiais do Testículo Limite: Feminino / Humanos / Masculino Idioma: Inglês Revista: Arch Gynecol Obstet Assunto da revista: Ginecologia / Obstetrícia Ano de publicação: 2018 Tipo de documento: Artigo País de afiliação: Espanha