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[Advances in studies of ileal apical sodium-dependent bile acid transporter].
Yao Xue Xue Bao ; 52(2): 189-97, 2017 Feb.
Artigo em Chinês | MEDLINE | ID: mdl-29979499
Bile acids play critical roles in the regulation of metabolism and absorption of lipids. The ileal apical sodium-dependent bile acid transporter (ASBT) located at the enterocyte brush border is responsible for the reuptake of bile acids and the maintenance of bile acid homeostasis. Recently, a number of investigations have been made concerning the regulation and control of ASBT and the relationship between ASBT and intestinal inflammation, tumorigenesis, diabetes mellitus and hyperlipemia, which suggests ASBT as a potential therapeutic target of these diseases. In this review, advances in the study of above-mentioned issues were summarized.
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Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Ácidos e Sais Biliares / Transportadores de Ânions Orgânicos Dependentes de Sódio / Simportadores / Íleo Limite: Humanos Idioma: Chinês Revista: Yao Xue Xue Bao Ano de publicação: 2017 Tipo de documento: Artigo