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Stem cell functionality is microenvironmentally defined during tumour expansion and therapy response in colon cancer.
Lenos, Kristiaan J; Miedema, Daniël M; Lodestijn, Sophie C; Nijman, Lisanne E; van den Bosch, Tom; Romero Ros, Xavier; Lourenço, Filipe C; Lecca, Maria C; van der Heijden, Maartje; van Neerven, Sanne M; van Oort, Anita; Leveille, Nicolas; Adam, Ronja S; de Sousa E Melo, Felipe; Otten, Joy; Veerman, Patrick; Hypolite, Guillaume; Koens, Lianne; Lyons, Scott K; Stassi, Giorgio; Winton, Douglas J; Medema, Jan Paul; Morrissey, Edward; Bijlsma, Maarten F; Vermeulen, Louis.
Afiliação
  • Lenos KJ; Amsterdam UMC, University of Amsterdam, LEXOR, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam and Amsterdam Gastroenterology & Metabolism, Amsterdam, The Netherlands.
  • Miedema DM; Amsterdam UMC, University of Amsterdam, LEXOR, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam and Amsterdam Gastroenterology & Metabolism, Amsterdam, The Netherlands.
  • Lodestijn SC; Amsterdam UMC, University of Amsterdam, LEXOR, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam and Amsterdam Gastroenterology & Metabolism, Amsterdam, The Netherlands.
  • Nijman LE; Amsterdam UMC, University of Amsterdam, LEXOR, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam and Amsterdam Gastroenterology & Metabolism, Amsterdam, The Netherlands.
  • van den Bosch T; Amsterdam UMC, University of Amsterdam, LEXOR, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam and Amsterdam Gastroenterology & Metabolism, Amsterdam, The Netherlands.
  • Romero Ros X; Amsterdam UMC, University of Amsterdam, LEXOR, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam and Amsterdam Gastroenterology & Metabolism, Amsterdam, The Netherlands.
  • Lourenço FC; Cancer Research UK, Cambridge Institute, University of Cambridge, Cambridge, UK.
  • Lecca MC; Amsterdam UMC, University of Amsterdam, LEXOR, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam and Amsterdam Gastroenterology & Metabolism, Amsterdam, The Netherlands.
  • van der Heijden M; Amsterdam UMC, University of Amsterdam, LEXOR, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam and Amsterdam Gastroenterology & Metabolism, Amsterdam, The Netherlands.
  • van Neerven SM; Amsterdam UMC, University of Amsterdam, LEXOR, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam and Amsterdam Gastroenterology & Metabolism, Amsterdam, The Netherlands.
  • van Oort A; Amsterdam UMC, University of Amsterdam, LEXOR, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam and Amsterdam Gastroenterology & Metabolism, Amsterdam, The Netherlands.
  • Leveille N; Amsterdam UMC, University of Amsterdam, LEXOR, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam and Amsterdam Gastroenterology & Metabolism, Amsterdam, The Netherlands.
  • Adam RS; Amsterdam UMC, University of Amsterdam, LEXOR, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam and Amsterdam Gastroenterology & Metabolism, Amsterdam, The Netherlands.
  • de Sousa E Melo F; Department of Discovery Oncology, Genentech, South San Francisco, CA, USA.
  • Otten J; Amsterdam UMC, University of Amsterdam, LEXOR, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam and Amsterdam Gastroenterology & Metabolism, Amsterdam, The Netherlands.
  • Veerman P; Amsterdam UMC, University of Amsterdam, LEXOR, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam and Amsterdam Gastroenterology & Metabolism, Amsterdam, The Netherlands.
  • Hypolite G; Amsterdam UMC, University of Amsterdam, LEXOR, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam and Amsterdam Gastroenterology & Metabolism, Amsterdam, The Netherlands.
  • Koens L; Department of Pathology, Academic Medical Center, Amsterdam, The Netherlands.
  • Lyons SK; Preclinical Imaging, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
  • Stassi G; Cellular & Molecular Pathophysiology Laboratory, Department of Surgical & Oncological Sciences, University of Palermo, Palermo, Italy.
  • Winton DJ; Cancer Research UK, Cambridge Institute, University of Cambridge, Cambridge, UK.
  • Medema JP; Amsterdam UMC, University of Amsterdam, LEXOR, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam and Amsterdam Gastroenterology & Metabolism, Amsterdam, The Netherlands.
  • Morrissey E; MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford, UK.
  • Bijlsma MF; Amsterdam UMC, University of Amsterdam, LEXOR, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam and Amsterdam Gastroenterology & Metabolism, Amsterdam, The Netherlands.
  • Vermeulen L; Amsterdam UMC, University of Amsterdam, LEXOR, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam and Amsterdam Gastroenterology & Metabolism, Amsterdam, The Netherlands. l.vermeulen@amc.uva.nl.
Nat Cell Biol ; 20(10): 1193-1202, 2018 10.
Article em En | MEDLINE | ID: mdl-30177776
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Protocolos de Quimioterapia Combinada Antineoplásica / Neoplasias do Colo / Ensaios Antitumorais Modelo de Xenoenxerto / Proliferação de Células / Microambiente Tumoral Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Nat Cell Biol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Holanda País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Protocolos de Quimioterapia Combinada Antineoplásica / Neoplasias do Colo / Ensaios Antitumorais Modelo de Xenoenxerto / Proliferação de Células / Microambiente Tumoral Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Nat Cell Biol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Holanda País de publicação: Reino Unido