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A review of the ethnopharmacology, phytochemistry, and pharmacology of Changium smyrnioides Wolff.
J Nat Med ; 73(1): 1-10, 2019 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-30182179
ABSTRACT
Changium smyrnioides Wolff is a monotypic species of the genus Changium Wolff which is only found in eastern China. C. smyrnioides has been used as a traditional medicine for ages to treat cough, vomiting, nausea, megrim, and carbuncle. It is also widely used to brew medicated liquor and health tea with other herbs in order to moisten the lungs and nourish blood and yin. This review comprehensively summarizes the up-to-date information on the botanical characterization, distribution, traditional uses, ethnopharmacology, phytochemistry, pharmacology, and toxicity of C. smyrnioides based on studies published in recent years. Phytochemical investigations have revealed that phenylpropanoids, volatile oils, fatty acids, phytosterols, and other bioactive compounds are contained in C. smyrnioides. Crude extracts and monomeric compounds isolated from C. smyrnioides have significant effects on the respiratory, immune, and vascular systems and exhibit favourable activities such as antitussive, eliminating phlegm, anti-asthmatic, immunoregulatory, antioxidant, anti-tumor, anti-fatigue, anti-hypoxia, and anti-atherosclerotic effects. C. smyrnioides is a promising medicinal herb with immense therapeutic and health-promoting effects. Therefore, further studies on the bioactive compounds and mechanisms of C. smyrnioides are necessary. Additional clinical and toxicological studies are warranted to evaluate its safety.
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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Plantas Medicinais / Extratos Vegetais / Apiaceae / Etnofarmacologia / Compostos Fitoquímicos Limite: Animais / Humanos Idioma: Inglês Revista: J Nat Med Assunto da revista: Terapias Complementares Ano de publicação: 2019 Tipo de documento: Artigo País de afiliação: China