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Cardiac troponin and natriuretic peptide analytical interferences from hemolysis and biotin: educational aids from the IFCC Committee on Cardiac Biomarkers (IFCC C-CB).
Clin Chem Lab Med ; 57(5): 633-640, 2019 04 24.
Artigo em Inglês | MEDLINE | ID: mdl-30291783
ABSTRACT
Two interferences recently brought to the forefront as patient safety issues include hemolysis (hemoglobin) and biotin (vitamin B7). The International Federation for Clinical Chemistry Committee on Cardiac Biomarkers (IFCC-CB) obtained input from a majority of cTn and NP assay manufacturers to collate information related to high-sensitivity (hs)-cTnI, hs-cTnT, contemporary, and POC cTn assays, and NP assays interferences due to hemolysis and biotin. The information contained in these tables was designed as educational tools to aid laboratory professionals and clinicians in troubleshooting cardiac biomarker analytical results that are discordant with the clinical situation.
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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Análise Química do Sangue / Troponina I / Troponina T / Peptídeo Natriurético Encefálico Limite: Humanos Idioma: Inglês Revista: Clin Chem Lab Med Assunto da revista: Química Clínica / Técnicas e Procedimentos de Laboratório Ano de publicação: 2019 Tipo de documento: Artigo País de afiliação: Estados Unidos