Drug-induced aortitis in a patient with ovarian cancer treated with bevacizumab combination therapy.
Taiwan J Obstet Gynecol
; 57(5): 750-752, 2018 Oct.
Article
em En
| MEDLINE
| ID: mdl-30342665
ABSTRACT
OBJECTIVE:
To review and evaluate drug-induced vasculitis, which is an extremely rare complication of chemotherapy. CASE REPORT A 47-year-old woman with ovarian cancer developed aortitis during bevacizumab combination chemotherapy. Contract-enhanced CT showed concentric thickening of the descending aorta. Antibiotics were administered, but a repeat CE-CT scan showed no resolution of the aortitis. To treat the aortitis, she was started on oral prednisolone. A subsequent CE-CT scan showed no signs of aortitis. She was thus re-started on a modified chemotherapy regimen.CONCLUSION:
Aortitis should be considered in patients receiving bevacizumab combination therapy who develop persistent fever and upper-abdominal pain. Contrast-enhanced CT is useful for detecting drug-induced aortitis.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Ovarianas
/
Aortite
/
Bevacizumab
Limite:
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Taiwan J Obstet Gynecol
Assunto da revista:
GINECOLOGIA
/
OBSTETRICIA
Ano de publicação:
2018
Tipo de documento:
Article