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Structural insights into the subtype-selective antagonist binding to the M2 muscarinic receptor.
Suno, Ryoji; Lee, Sangbae; Maeda, Shoji; Yasuda, Satoshi; Yamashita, Keitaro; Hirata, Kunio; Horita, Shoichiro; Tawaramoto, Maki S; Tsujimoto, Hirokazu; Murata, Takeshi; Kinoshita, Masahiro; Yamamoto, Masaki; Kobilka, Brian K; Vaidehi, Nagarajan; Iwata, So; Kobayashi, Takuya.
Afiliação
  • Suno R; Department of Cell Biology and Medical Chemistry, Graduate School of Medicine, Kyoto University, Konoe-cho, Yoshida, Sakyo-ku, Kyoto, Japan. r.suno@mfour.med.kyoto-u.ac.jp.
  • Lee S; Department of Molecular Imaging and Therapy, Beckman Research Institute of the City of Hope, Duarte, CA, USA.
  • Maeda S; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.
  • Yasuda S; Graduate School of Science and Molecular Chirality Research Center, Chiba University, Inage, Chiba, Japan.
  • Yamashita K; RIKEN, SPring-8 Center, Hyogo, Japan.
  • Hirata K; RIKEN, SPring-8 Center, Hyogo, Japan.
  • Horita S; Japan Science and Technology Agency, Precursory Research for Embryonic Science and Technology (PRESTO), Kawaguchi, Saitama, Japan.
  • Tawaramoto MS; Department of Cell Biology and Medical Chemistry, Graduate School of Medicine, Kyoto University, Konoe-cho, Yoshida, Sakyo-ku, Kyoto, Japan.
  • Tsujimoto H; Department of Cell Biology and Medical Chemistry, Graduate School of Medicine, Kyoto University, Konoe-cho, Yoshida, Sakyo-ku, Kyoto, Japan.
  • Murata T; Department of Cell Biology and Medical Chemistry, Graduate School of Medicine, Kyoto University, Konoe-cho, Yoshida, Sakyo-ku, Kyoto, Japan.
  • Kinoshita M; Graduate School of Science and Molecular Chirality Research Center, Chiba University, Inage, Chiba, Japan.
  • Yamamoto M; Japan Science and Technology Agency, Precursory Research for Embryonic Science and Technology (PRESTO), Kawaguchi, Saitama, Japan.
  • Kobilka BK; Institute of Advanced Energy and Graduate School of Energy Science, Kyoto University, Uji, Kyoto, Japan.
  • Vaidehi N; RIKEN, SPring-8 Center, Hyogo, Japan.
  • Iwata S; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.
  • Kobayashi T; Department of Molecular Imaging and Therapy, Beckman Research Institute of the City of Hope, Duarte, CA, USA.
Nat Chem Biol ; 14(12): 1150-1158, 2018 12.
Article em En | MEDLINE | ID: mdl-30420692

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirenzepina / Antagonistas Muscarínicos / Receptor Muscarínico M2 Limite: Humans Idioma: En Revista: Nat Chem Biol Assunto da revista: BIOLOGIA / QUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirenzepina / Antagonistas Muscarínicos / Receptor Muscarínico M2 Limite: Humans Idioma: En Revista: Nat Chem Biol Assunto da revista: BIOLOGIA / QUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão País de publicação: Estados Unidos