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Clinical and dermoscopic features associated with lichen planus-like keratoses that undergo skin biopsy: A single-center, observational study.
Liopyris, Konstantinos; Navarrete-Dechent, Cristian; Dusza, Stephen W; Marghoob, Ashfaq A; Deng, Liang; Wilson, Barbara B; Marchetti, Michael A.
Afiliação
  • Liopyris K; Dermatology Service, Memorial Sloan Kettering Cancer Center, New York City, New York, USA.
  • Navarrete-Dechent C; Department of Dermatology, A. Syggros Hospital, University of Athens, Athens, Greece.
  • Dusza SW; Dermatology Service, Memorial Sloan Kettering Cancer Center, New York City, New York, USA.
  • Marghoob AA; Department of Dermatology, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
  • Deng L; Dermatology Service, Memorial Sloan Kettering Cancer Center, New York City, New York, USA.
  • Wilson BB; Dermatology Service, Memorial Sloan Kettering Cancer Center, New York City, New York, USA.
  • Marchetti MA; Dermatology Service, Memorial Sloan Kettering Cancer Center, New York City, New York, USA.
Australas J Dermatol ; 60(2): e119-e126, 2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-30450536
ABSTRACT
BACKGROUND/

OBJECTIVES:

Lichen planus-like keratoses (LPLK) are benign skin lesions that can mimic malignancy; the clinical and dermoscopic features distinguishing lichen planus-like keratoses from skin tumors have not been extensively studied. The objective of this study was to identify dermoscopic features that may prevent unnecessary biopsies of lichen planus-like keratoses.

METHODS:

Retrospective, single-center, observational study of biopsied skin lesions at a tertiary center. We compared 355 lichen planus-like keratoses to 118 non-lichen planus-like keratoses lesions with lichen planus-like keratosis in the differential diagnosis biopsied from August 1, 2015, to December 31, 2016. The investigators were blinded to the diagnosis of the lesions.

RESULTS:

Lichen planus-like keratoses were most frequently non-pigmented (61.7%), truncal (52.1%), and on sun-damaged skin (69.6%); the majority occurred in Whites (95.5%) and females (62.8%). Dermoscopically, lichen planus-like keratoses were more likely than non-lichen planus-like keratoses to have scale (42.5% vs 31.4%, P = 0.03) and orange colour (8.2% vs 0.9%, P = 0.01). Among lesions with peppering (n = 76; 63 lichen planus-like keratoses and 13 non-lichen planus-like keratoses), coarse ± fine peppering (73% vs 38.5%, P = 0.02) and peppering as the only feature (34.9% vs 0%, P = 0.01) were associated with lichen planus-like keratoses.

CONCLUSIONS:

Lichen planus-like keratoses can be challenging to distinguish from benign and malignant skin tumors. The presence of dermoscopic scale and orange colour may aid in the recognition of lichen planus-like keratosis. Coarse peppering and the presence of peppering as the only dermoscopic feature may further aid the identification of pigmented lichen planus-like keratoses.
Assuntos
Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Dermoscopia / Ceratose / Líquen Plano Limite: Idoso / Feminino / Humanos / Masculino Idioma: Inglês Revista: Australas J Dermatol Ano de publicação: 2019 Tipo de documento: Artigo País de afiliação: Estados Unidos

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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Dermoscopia / Ceratose / Líquen Plano Limite: Idoso / Feminino / Humanos / Masculino Idioma: Inglês Revista: Australas J Dermatol Ano de publicação: 2019 Tipo de documento: Artigo País de afiliação: Estados Unidos