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Anti-N-methyl-D-aspartate receptor encephalitis: A case report.
Medicine (Baltimore) ; 97(50): e13625, 2018 12.
Artigo em Inglês | MEDLINE | ID: mdl-30558047
ABSTRACT
RATIONALE Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is an auto-immune and paraneoplastic encephalitis with prominent neuropsychiatric manifestations. The N-methyl-D-aspartate receptor is located in the forebrain and hippocampus and plays a role in learning and memory. PATIENT CONCERNS A 29-year-old female patient with anti-NMDAR encephalitis, was reported and we also reviewed the literature and summarised the characteristics of the cases. DIAGNOSES In the present study, we reported 1 patient with anti-NMDAR encephalitis diagnosed by the detection of anti-NMDAR antibodies in serum and cerebrospinal fluid (CSF).

INTERVENTIONS:

The patient received glucocorticoids and anti-epilepsy treatment as well as human immunoglobulin treatment.

OUTCOMES:

After treatment, the patient gradually regained consciousness and was discharged after 3 months of rehabilitation. At the follow-up 2 months later, the patient had the sequelae of memory impairment and limb movement disorders. LESSONS An accurate early diagnosis and active treatment are crucial to the improvement in the prognosis of patients with anti-NMDAR receptor encephalitis.
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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Imunoglobulinas / Receptores de N-Metil-D-Aspartato / Encefalite Antirreceptor de N-Metil-D-Aspartato / Glucocorticoides / Anticonvulsivantes Tipo de estudo: Relato de casos Aspecto clínico: Prognóstico Limite: Adulto / Feminino / Humanos Idioma: Inglês Revista: Medicine (Baltimore) Ano de publicação: 2018 Tipo de documento: Artigo