Insights into the anti-infective properties of prodiginines.
Appl Microbiol Biotechnol
; 103(7): 2873-2887, 2019 Apr.
Article
em En
| MEDLINE
| ID: mdl-30761415
ABSTRACT
Prodiginines are a large family of tripyrrole alkaloids that contain natural members produced by various bacteria and non-natural members obtained from chemical synthesis, enzymatic synthesis, and mutasynthesis. These compounds have attracted a great deal of attention due to their wide range of fascinating properties including anti-infective, anticancer, and immunosuppressive activities. In consideration of the great need for novel and effective anti-infective agents, this review is mainly focused on the current status of research on the anti-infective properties of prodiginines, highlighting their antibacterial, antifungal, antiprotozoal, anti-larval, and antiviral activities. Additionally, the multiple mechanisms by which prodiginines exert their anti-infective effects will also be discussed.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Prodigiosina
/
Anti-Infecciosos
Limite:
Animals
Idioma:
En
Revista:
Appl Microbiol Biotechnol
Ano de publicação:
2019
Tipo de documento:
Article
País de publicação:
ALEMANHA
/
ALEMANIA
/
DE
/
DEUSTCHLAND
/
GERMANY