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USP39 regulates DNA damage response and chemo-radiation resistance by deubiquitinating and stabilizing CHK2.
Wu, Jinhuan; Chen, Yuping; Geng, Guohe; Li, Lei; Yin, Ping; Nowsheen, Somaira; Li, Yunhui; Wu, Chenming; Liu, Jiaqi; Zhao, Fei; Kim, Wootae; Zhou, Qin; Huang, Jinzhou; Guo, Guijie; Zhang, Chao; Tu, Xinyi; Gao, Xiumei; Lou, Zhenkun; Luo, Kuntian; Qiao, Haixuan; Yuan, Jian.
Afiliação
  • Wu J; Research Center for Translational Medicine, East Hospital, Tongji University School of Medicine, Shanghai, 200120, China; Key Laboratory of Arrhythmias of the Ministry of Education of China, East Hospital, Tongji University School of Medicine, Shanghai, 200120, China; School of Biomedical Engineerin
  • Chen Y; Research Center for Translational Medicine, East Hospital, Tongji University School of Medicine, Shanghai, 200120, China; Key Laboratory of Arrhythmias of the Ministry of Education of China, East Hospital, Tongji University School of Medicine, Shanghai, 200120, China.
  • Geng G; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
  • Li L; Research Center for Translational Medicine, East Hospital, Tongji University School of Medicine, Shanghai, 200120, China; Key Laboratory of Arrhythmias of the Ministry of Education of China, East Hospital, Tongji University School of Medicine, Shanghai, 200120, China.
  • Yin P; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.
  • Nowsheen S; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.
  • Li Y; Research Center for Translational Medicine, East Hospital, Tongji University School of Medicine, Shanghai, 200120, China; Key Laboratory of Arrhythmias of the Ministry of Education of China, East Hospital, Tongji University School of Medicine, Shanghai, 200120, China.
  • Wu C; Research Center for Translational Medicine, East Hospital, Tongji University School of Medicine, Shanghai, 200120, China; Key Laboratory of Arrhythmias of the Ministry of Education of China, East Hospital, Tongji University School of Medicine, Shanghai, 200120, China.
  • Liu J; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.
  • Zhao F; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.
  • Kim W; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.
  • Zhou Q; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.
  • Huang J; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.
  • Guo G; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.
  • Zhang C; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.
  • Tu X; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.
  • Gao X; Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 300193, Tianjin, China.
  • Lou Z; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA; Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA. Electronic address: Lou.zhenkun@mayo.edu.
  • Luo K; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA; Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA. Electronic address: Luo.kuntian@mayo.edu.
  • Qiao H; School of Biomedical Engineering and Technology, Tianjin Medical University, 300070, Tianjin, China. Electronic address: qiaohaixuan@aliyun.com.
  • Yuan J; Research Center for Translational Medicine, East Hospital, Tongji University School of Medicine, Shanghai, 200120, China; Key Laboratory of Arrhythmias of the Ministry of Education of China, East Hospital, Tongji University School of Medicine, Shanghai, 200120, China. Electronic address: yuanjian229
Cancer Lett ; 449: 114-124, 2019 05 01.
Article em En | MEDLINE | ID: mdl-30771428
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tolerância a Radiação / Resistencia a Medicamentos Antineoplásicos / Proteases Específicas de Ubiquitina / Quinase do Ponto de Checagem 2 / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Cancer Lett Ano de publicação: 2019 Tipo de documento: Article País de publicação: Irlanda
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tolerância a Radiação / Resistencia a Medicamentos Antineoplásicos / Proteases Específicas de Ubiquitina / Quinase do Ponto de Checagem 2 / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Cancer Lett Ano de publicação: 2019 Tipo de documento: Article País de publicação: Irlanda