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Role of Ancillary Techniques in Gynecologic Cytopathology Specimens.
Acta Cytol ; 64(1-2): 63-70, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-30889579
ABSTRACT
The association between high-risk genotypes of human papillomavirus (hr-HPV) and cervical cancer is well established. As hr-HPV testing is rapidly becoming a part of routine cervical cancer screening, either in conjunction with cytology or as primary testing, the management of hr-HPV-positive women has to be tailored in a way that increases the detection of cervical abnormalities while decreasing unnecessary colposcopic biopsies or other invasive procedures. In this review, we discuss the overall utility and strategies of hr-HPV testing, as well as the advantages and limitations of potential triage strategies for hr-HPV-positive women, including HPV genotyping, p16/Ki-67 dual staining, and methylation assays.
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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Papillomaviridae / Neoplasias do Colo do Útero / Citodiagnóstico / Infecções por Papillomavirus Aspecto clínico: Diagnóstico / Etiologia Limite: Adulto / Feminino / Humanos / Meia-Idade Idioma: Inglês Revista: Acta Cytol Ano de publicação: 2020 Tipo de documento: Artigo País de afiliação: Estados Unidos