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Dual platelet antiaggregation therapy after myocardial revascularization surgery.
Feitosa, Mateus Paiva Marques; Soffiatti, Carla David; Linhares Filho, Jaime Paula Pessoa; Batista, Daniel Valente; Lobo Filho, Heraldo Guedis; Lima, Eduardo Gomes; Serrano Júnior, Carlos Vicente.
Afiliação
  • Feitosa MPM; Cardiology resident at the Heart Institute of the Hospital das Clínicas of the Faculty of Medicine of the University of São Paulo, São Paulo, Brasil.
  • Soffiatti CD; Cardiology resident at the Heart Institute of the Hospital das Clínicas of the Faculty of Medicine of the University of São Paulo, São Paulo, Brasil.
  • Linhares Filho JPP; Department of Atherosclerosis of the Heart Institute of the Hospital das Clínicas of the Faculty of Medicine of the University of São Paulo, São Paulo, Brasil.
  • Batista DV; Department of Atherosclerosis of the Heart Institute of the Hospital das Clínicas of the Faculty of Medicine of the University of São Paulo, São Paulo, Brasil.
  • Lobo Filho HG; Department of Surgery of the Faculty of Medicine of the Federal University of Ceará, Ceará, Brasil.
  • Lima EG; Department of Atherosclerosis of the Heart Institute of the Hospital das Clínicas of the Faculty of Medicine of the University of São Paulo, São Paulo, Brasil.
  • Serrano Júnior CV; Department of Atherosclerosis of the Heart Institute of the Hospital das Clínicas of the Faculty of Medicine of the University of São Paulo, São Paulo, Brasil.
Rev Assoc Med Bras (1992) ; 65(3): 316-318, 2019 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-30994825
ABSTRACT
Coronary artery bypass graft (CABG) is a consolidated treatment in patients with coronary artery disease (CAD) for both symptom control and improvement of prognosis. The patency of venous grafts is still the most vulnerable point of the surgical treatment since it presents a high prevalence of occlusion both in the immediate postoperative period and in the long-term follow-up. Aspirin plays a well-established role in this setting, and for a long time, clopidogrel use has been restricted to patients allergic to aspirin. Recently, subgroup analyses of studies with different anti-platelet therapies have shown reduced mortality and cardiovascular events in patients on dual anti-platelet antiplatelet therapy (DAPT) undergoing CABG, although such studies have not been designed to evaluate this patient profile. However, there is still an insufficient number of randomized studies using DAPT in this context, resulting in a disagreement between the European and American cardiology societies guidelines regarding their indication and generating doubts in clinical practice.
Assuntos
Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Grau de Desobstrução Vascular / Inibidores da Agregação de Plaquetas / Ponte de Artéria Coronária / Oclusão de Enxerto Vascular Limite: Humanos Idioma: Inglês Revista: Rev Assoc Med Bras (1992) Ano de publicação: 2019 Tipo de documento: Artigo País de afiliação: Brasil

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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Grau de Desobstrução Vascular / Inibidores da Agregação de Plaquetas / Ponte de Artéria Coronária / Oclusão de Enxerto Vascular Limite: Humanos Idioma: Inglês Revista: Rev Assoc Med Bras (1992) Ano de publicação: 2019 Tipo de documento: Artigo País de afiliação: Brasil