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Relation of multicenter automatic defibrillator implantation trial implantable cardioverter-defibrillator score with long-term cardiovascular events in patients with implantable cardioverter-defibrillator.
Uslu, Abdulkadir; Dogan, Cem; Duman, Hakan; Tanboga, Ibrahim Halil; Askin, Lutfu; Sevimli, Serdar.
Afiliação
  • Uslu A; Department of Cardiology, University of Health Sciences, Kartal Kosuyolu Training and Research Hospital, Istanbul, Turkey.
  • Dogan C; Department of Cardiology, University of Health Sciences, Kartal Kosuyolu Training and Research Hospital, Istanbul, Turkey.
  • Duman H; Department of Cardiology, Rize Recep Tayyip Erdogan University, Research and Training Hospital, Rize, Turkey.
  • Tanboga IH; Department of Cardiology Hisar Intercontinental Hospital, Istanbul, Turkey.
  • Askin L; Department of Cardiology, University of Health Sciences, Adiyaman Training and Research Hospital, Adiyaman, Turkey.
  • Sevimli S; Department of Cardiology, Ataturk University Yakutiye Training and Research Hospital, Erzurum, Turkey.
North Clin Istanb ; 6(1): 40-47, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31180377
ABSTRACT

OBJECTIVE:

To test the hypothesis that multicenter automatic defibrillator implantation trial (MADIT) - implantable cardioverter-defibrillator (ICD) scores predict replacement requirement and appropriate shock in a mixed population including both primary and secondary prevention and long-term adverse cardiovascular events.

METHODS:

The study has a retrospective design. Patients who were implanted with ICD in the cardiology clinic of Atatürk University Faculty of Medicine between 2000 and 2013 were included in the study. For this purpose, 1394 patients who were implanted with a device in our clinic were reviewed. Then, those who were implanted with permanent pacemaker (n=1005), cardiac resynchronization treatment (CRT) (n=45) and CRT-ICD (n=198) were excluded.

RESULTS:

A total of 146 patients (98 males, 67.1%) with a mean age of 61.1 (±14.8) years were recruited. The median follow-up time was 21.5 months (mean 30.6±25.9 months; minimum 4 months, and maximum 120 months). The median MADIT-ICD scores in the patients were 2. MADIT-ICD scores were categorized as low in 15.1%, intermediate in 57.5%, and high score in 27.4% of patients. Accordingly, MADIT-ICD scores (1.29 [1.00-1.68], p=0.050), hemoglobin (0.86 [0.75-0.99], p=0.047), and left ventricular ejection fraction (EF) (0.97 [0.94-0.99], p=0.023) were determined as independent predictors of major adverse cardiovascular events in the long-term follow-up of ICD-implanted population.

CONCLUSION:

In this study, we showed that there was an independent association of long-term adverse cardiovascular events with MADIT-ICD score, hemoglobin, and EF in patients implanted with ICD.
Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Idioma: Inglês Revista: North Clin Istanb Ano de publicação: 2019 Tipo de documento: Artigo País de afiliação: Turquia

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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Idioma: Inglês Revista: North Clin Istanb Ano de publicação: 2019 Tipo de documento: Artigo País de afiliação: Turquia