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Optimization of LpxC Inhibitors for Antibacterial Activity and Cardiovascular Safety.
Cohen, Frederick; Aggen, James B; Andrews, Logan D; Assar, Zahra; Boggs, Jen; Choi, Taylor; Dozzo, Paola; Easterday, Ashton N; Haglund, Cat M; Hildebrandt, Darin J; Holt, Melissa C; Joly, Kristin; Jubb, Adrian; Kamal, Zeeshan; Kane, Timothy R; Konradi, Andrei W; Krause, Kevin M; Linsell, Martin S; Machajewski, Timothy D; Miroshnikova, Olga; Moser, Heinz E; Nieto, Vincent; Phan, Thu; Plato, Craig; Serio, Alisa W; Seroogy, Julie; Shakhmin, Anton; Stein, Adam J; Sun, Alex D; Sviridov, Serguei; Wang, Zhan; Wlasichuk, Kenneth; Yang, Wen; Zhou, Xiaoming; Zhu, Hai; Cirz, Ryan T.
Afiliação
  • Cohen F; Achaogen Inc., 1 Tower Place, Suite 400, South San Francisco, CA, 94080, USA.
  • Aggen JB; Achaogen Inc., 1 Tower Place, Suite 400, South San Francisco, CA, 94080, USA.
  • Andrews LD; Achaogen Inc., 1 Tower Place, Suite 400, South San Francisco, CA, 94080, USA.
  • Assar Z; Cayman Chemical Co., 1180 East Ellsworth, Ann Arbor, MI, 48108, USA.
  • Boggs J; Achaogen Inc., 1 Tower Place, Suite 400, South San Francisco, CA, 94080, USA.
  • Choi T; Achaogen Inc., 1 Tower Place, Suite 400, South San Francisco, CA, 94080, USA.
  • Dozzo P; Achaogen Inc., 1 Tower Place, Suite 400, South San Francisco, CA, 94080, USA.
  • Easterday AN; Achaogen Inc., 1 Tower Place, Suite 400, South San Francisco, CA, 94080, USA.
  • Haglund CM; Achaogen Inc., 1 Tower Place, Suite 400, South San Francisco, CA, 94080, USA.
  • Hildebrandt DJ; Achaogen Inc., 1 Tower Place, Suite 400, South San Francisco, CA, 94080, USA.
  • Holt MC; Cayman Chemical Co., 1180 East Ellsworth, Ann Arbor, MI, 48108, USA.
  • Joly K; Plato BioPharma Inc., 7581 West 103rd Avenue, Unit 300, Westminster, CO, 80021, USA.
  • Jubb A; Achaogen Inc., 1 Tower Place, Suite 400, South San Francisco, CA, 94080, USA.
  • Kamal Z; Nanosyn Inc., 3100 Central Expressway, Santa Clara, CA, 95051, USA.
  • Kane TR; Achaogen Inc., 1 Tower Place, Suite 400, South San Francisco, CA, 94080, USA.
  • Konradi AW; Konradi Molecular, 30 Victoria Road, Burlingame, CA, 94010, USA.
  • Krause KM; Achaogen Inc., 1 Tower Place, Suite 400, South San Francisco, CA, 94080, USA.
  • Linsell MS; Achaogen Inc., 1 Tower Place, Suite 400, South San Francisco, CA, 94080, USA.
  • Machajewski TD; Achaogen Inc., 1 Tower Place, Suite 400, South San Francisco, CA, 94080, USA.
  • Miroshnikova O; Nanosyn Inc., 3100 Central Expressway, Santa Clara, CA, 95051, USA.
  • Moser HE; Achaogen Inc., 1 Tower Place, Suite 400, South San Francisco, CA, 94080, USA.
  • Nieto V; Achaogen Inc., 1 Tower Place, Suite 400, South San Francisco, CA, 94080, USA.
  • Phan T; Nanosyn Inc., 3100 Central Expressway, Santa Clara, CA, 95051, USA.
  • Plato C; Plato BioPharma Inc., 7581 West 103rd Avenue, Unit 300, Westminster, CO, 80021, USA.
  • Serio AW; Achaogen Inc., 1 Tower Place, Suite 400, South San Francisco, CA, 94080, USA.
  • Seroogy J; Achaogen Inc., 1 Tower Place, Suite 400, South San Francisco, CA, 94080, USA.
  • Shakhmin A; Nanosyn Inc., 3100 Central Expressway, Santa Clara, CA, 95051, USA.
  • Stein AJ; Cayman Chemical Co., 1180 East Ellsworth, Ann Arbor, MI, 48108, USA.
  • Sun AD; Nanosyn Inc., 3100 Central Expressway, Santa Clara, CA, 95051, USA.
  • Sviridov S; Nanosyn Inc., 3100 Central Expressway, Santa Clara, CA, 95051, USA.
  • Wang Z; Nanosyn Inc., 3100 Central Expressway, Santa Clara, CA, 95051, USA.
  • Wlasichuk K; Achaogen Inc., 1 Tower Place, Suite 400, South San Francisco, CA, 94080, USA.
  • Yang W; Nanosyn Inc., 3100 Central Expressway, Santa Clara, CA, 95051, USA.
  • Zhou X; Pharmaron Inc., 6 Tai-He Road, BDA, Beijing, 100176, China.
  • Zhu H; Nanosyn Inc., 3100 Central Expressway, Santa Clara, CA, 95051, USA.
  • Cirz RT; Achaogen Inc., 1 Tower Place, Suite 400, South San Francisco, CA, 94080, USA.
ChemMedChem ; 14(16): 1560-1572, 2019 08 20.
Article em En | MEDLINE | ID: mdl-31283109
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Di-Inos / Amidoidrolases / Coração / Ácidos Hidroxâmicos / Antibacterianos Limite: Animals Idioma: En Revista: ChemMedChem Assunto da revista: FARMACOLOGIA / QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Alemanha
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Di-Inos / Amidoidrolases / Coração / Ácidos Hidroxâmicos / Antibacterianos Limite: Animals Idioma: En Revista: ChemMedChem Assunto da revista: FARMACOLOGIA / QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Alemanha