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A supersensitive biosensor based on MoS2 nanosheet arrays for the real-time detection of H2O2 secreted from living cells.
Chem Commun (Camb) ; 55(65): 9653-9656, 2019 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-31342021
ABSTRACT
The fast and accurate real-time monitoring of hydrogen peroxide (H2O2) secreted from living cells plays a critical role in clinical diagnosis and management. Herein, we report low-cost and self-supported MoS2 nanosheet arrays for non-enzymatic eletrochemical H2O2 detection. Under the optimal test conditions, such MoS2 electrodes exhibit extremely promising electrocatalytic performance with a low detection limit of 1.0 µM (S/N = 3) and an excellent sensitivity of 5.3 mA mM-1 cm-2. Furthermore, the detection of the trace amount of H2O2 secreted from live A549 cancer cells was successfully performed with this biosensor.
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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Nanoestruturas / Dissulfetos / Peróxido de Hidrogênio / Molibdênio Aspecto clínico: Diagnóstico Limite: Humanos Idioma: Inglês Revista: Chem Commun (Camb) Assunto da revista: Química Ano de publicação: 2019 Tipo de documento: Artigo País de afiliação: China