Accuracy of Resting Energy Expenditure Predictive Equations in Patients With Cancer.
Nutr Clin Pract
; 34(6): 922-934, 2019 Dec.
Article
em En
| MEDLINE
| ID: mdl-31347209
ABSTRACT
BACKGROUND:
Our purpose was to assess the accuracy of resting energy expenditure (REE) equations in patients with newly diagnosed stage I-IV non-small cell lung, rectal, colon, renal, or pancreatic cancer.METHODS:
In this cross-sectional study, REE was measured using indirect calorimetry and compared with 23 equations. Agreement between measured and predicted REE was assessed via paired t-tests, Bland-Altman analysis, and percent of estimations ≤ 10% of measured values. Accuracy was measured among subgroups of body mass index (BMI), stage (I-III vs IV), and cancer type (lung, rectal, and colon) categories. Fat mass (FM) and fat-free mass (FFM) were assessed using dual x-ray absorptiometry.RESULTS:
Among 125 patients, most had lung, colon, or rectal cancer (92%, BMI 27.5 ± 5.6 kg/m2 , age 61 ± 11 years, REE 1629 ± 321 kcal/d). Thirteen (56.5%) equations yielded REE values different than measured (P < 0.05). Limits of agreement were wide for all equations, with Mifflin-St. Jeor equation having the smallest limits of agreement, -21.7% to 11.3% (-394 to 203 kcal/d). Equations with FFM were not more accurate except for one equation (Huang with body composition; bias, limits of agreement -0.3 ± 11.3% vs without body composition 2.3 ± 10.1%, P < 0.001). Bias in body composition equations was consistently positively correlated with age and frequently negatively correlated with FM. Bias and limits of agreement were similar among subgroups of patients.CONCLUSION:
REE cannot be accurately predicted on an individual level, and bias relates to age and FM.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Metabolismo Basal
/
Neoplasias
Tipo de estudo:
Health_economic_evaluation
/
Observational_studies
/
Prevalence_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adult
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Aged
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Aged80
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Nutr Clin Pract
Assunto da revista:
CIENCIAS DA NUTRICAO
/
ENFERMAGEM
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Canadá