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Contrast-enhanced ultrasonography of nasopharyngeal carcinoma: enhancement patterns and quantitative parameters.
Discov Med ; 27(150): 227-233, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-31421691


The aim of this study was to investigate the characteristics of nasopharyngeal carcinoma (NPC) using contrast-enhanced ultrasonography (CEUS), including the enhancement patterns and the quantitative parameters.


Having been scanned using conventional ultrasonography (US) and CEUS, every case was confirmed to be NPC under endoscopic biopsy, and no case received any anti-tumor treatment before CEUS examinations. Tumor/node/metastasis stages were determined in accordance with 2002 AJCC 6th edition. Contrast enhancement patterns and quantitative parameters were observed.


CEUS imaging of NPC showed that the tumor signal intensity enhanced early, rapidly, and remarkably, and decreased slowly later. The patterns of enhancement included spot/linear enhancement, peripheral enhancement, and mass enhancement, and two types of time intensity curves of NPC included type I and type II. There was a significant difference between peak intensity (PI) and T stage (P<0.05), whereas time-to-peak (TP) and slope did not show significant differences with T stage (P>0.05).


CEUS is feasible to be applied to the nasopharynx region. The use of CEUS makes it possible to observe vascular permeability of NPC. Our results suggest that the quantitative parameter PI of nasopharyngeal carcinoma is significantly different from T stages. Thus, PI may serve as a potential noninvasive radiological prognostic indicator for NPC.





Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Aumento da Imagem / Ultrassonografia / Meios de Contraste / Carcinoma Nasofaríngeo Aspecto clínico: Prognóstico Limite: Adulto / Feminino / Humanos / Masculino / Meia-Idade Idioma: Inglês Revista: Discov Med Ano de publicação: 2019 Tipo de documento: Artigo País de afiliação: China