BabaoDan cures hepatic encephalopathy by decreasing ammonia levels and alleviating inflammation in rats.

Lu, Lu; Wu, Chao; Lu, Bing-Jie; Xie, Dong; Wang, Zheng; Bahaji Azami, Nisma Lena; An, Yong-Tong; Wang, Hui-Jun; Ye, Guan; Sun, Ming-Yu

Lu, Lu; Wu, Chao; Lu, Bing-Jie; Xie, Dong; Wang, Zheng; Bahaji Azami, Nisma Lena; An, Yong-Tong; Wang, Hui-Jun; Ye, Guan; Sun, Ming-Yu.

Afiliação

Lu L; Shuguang Hospital, Key Laboratory of Liver and Kidney Diseases (Ministry of Education), Institute of Liver Diseases, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China; Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. Electronic address: 410947756
Wu C; Shuguang Hospital, Key Laboratory of Liver and Kidney Diseases (Ministry of Education), Institute of Liver Diseases, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China; Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. Electronic address: 127749601
Lu BJ; Shuguang Hospital, Key Laboratory of Liver and Kidney Diseases (Ministry of Education), Institute of Liver Diseases, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China; Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. Electronic address: dlbj7777@
Xie D; Shuguang Hospital, Key Laboratory of Liver and Kidney Diseases (Ministry of Education), Institute of Liver Diseases, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China; Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. Electronic address: xdieong@1
Wang Z; Shuguang Hospital, Key Laboratory of Liver and Kidney Diseases (Ministry of Education), Institute of Liver Diseases, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China; Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. Electronic address: ebonleo@1
Bahaji Azami NL; Shuguang Hospital, Key Laboratory of Liver and Kidney Diseases (Ministry of Education), Institute of Liver Diseases, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China; Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
An YT; Central Research Institute of Shanghai Pharmaceutical Group Co, Ltd, Shanghai, 201203, China. Electronic address: anyt@sphchina.com.
Wang HJ; Central Research Institute of Shanghai Pharmaceutical Group Co, Ltd, Shanghai, 201203, China. Electronic address: wanghuijun@sphchina.com.
Ye G; Central Research Institute of Shanghai Pharmaceutical Group Co, Ltd, Shanghai, 201203, China. Electronic address: yeg@sphchina.com.
Sun MY; Shuguang Hospital, Key Laboratory of Liver and Kidney Diseases (Ministry of Education), Institute of Liver Diseases, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China; Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. Electronic address: mysun248@

J Ethnopharmacol ; 249: 112301, 2020 Mar 01.

Article em En | MEDLINE | ID: mdl-31622746

Assuntos

Amônia/metabolismo; Anti-Inflamatórios/farmacologia; Encefalopatia Hepática/tratamento farmacológico; Inflamação/tratamento farmacológico; Fígado/efeitos dos fármacos; Animais; Modelos Animais de Doenças; Encefalopatia Hepática/metabolismo; Inflamação/metabolismo; Fígado/metabolismo; Falência Hepática Aguda/tratamento farmacológico; Falência Hepática Aguda/metabolismo; Macrófagos/efeitos dos fármacos; Macrófagos/metabolismo; Masculino; Fator 88 de Diferenciação Mieloide/metabolismo; NF-kappa B/metabolismo; Ratos; Ratos Wistar; Transdução de Sinais/efeitos dos fármacos; Receptor 4 Toll-Like/metabolismo; Fator de Necrose Tumoral alfa/metabolismo

Palavras-chave

Acrylamide (PubChem CID: 6579); Ammonia; Ammonium persulfate (PubChem CID: 62648); Babaodan; Carbon tetrachloride (PubChem CID: 5943); Chinese medicine; Chloroform (PubChem CID: 6212); Dimethyl sulfoxide (DMSO) (PubChem CID: 679); Disodium hydrogen phosphate (PubChem CID: 24203); Ethanol (PubChem CID: 702); Formaldehyde (PubChem CID: 712); Glycine (PubChemCID: 750); Hepatic encephalopathy; Immune; Inflammation; Macrophage; Methanol (PubChem CID: 887); Potassium chloride (PubChem CID: 4873); Potassium dihydrogen phosphate (PubChem CID: 516951); Sodium chloride (PubChem CID: 5234); Sodium dihydrogen phosphate (PubChem CID: 23672064); Sodium dodecyl sulfate (PubChem CID: 3423265); Thioacetamide (PubChem CID: 2723949); Tris (PubChem CID: 6503); Xylene (PubChem CID: 6850715)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encefalopatia Hepática / Amônia / Inflamação / Fígado / Anti-Inflamatórios Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Ethnopharmacol Ano de publicação: 2020 Tipo de documento: Article País de publicação: Irlanda

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