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A Simple Clinical Instrument to Predict the Survival Probability of Breast Cancer Patients Receiving Radiotherapy for Bone Metastases.
Anticancer Res ; 40(1): 367-371, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31892588
ABSTRACT

BACKGROUND/AIM:

Individualization of treatment may improve the outcome of patients with bone metastases from breast cancer. To support physicians when selecting individualized programs for these patients, a simple instrument for predicting survival was created.

PATIENTS AND METHODS:

In 126 female patients with breast cancer irradiated for bone metastases, 11 characteristics were evaluated with respect to survival.

RESULTS:

On Cox regression analysis, Eastern Cooperative Oncology Group performance score (0-1 vs. ≥2; p=0.032) and visceral metastases (absence vs. presence; p=0.017) were independently associated with survival and incorporated into the scoring instrument. Three prognostic groups (0, 1 or 2 points) were designated with 12-month survival rates of 38%, 57% and 91%, and 24-month survival rates of 32%, 36% and 80%, respectively (p<0.001).

CONCLUSION:

This easy-to-use scoring instrument allows physicians to estimate the lifespan of patients irradiated for bone metastases from breast cancer and can facilitate individualization of their treatment.
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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Neoplasias Ósseas / Neoplasias da Mama / Probabilidade / Estimativa de Kaplan-Meier Aspecto clínico: Predição / Prognóstico Limite: Idoso / Feminino / Humanos / Meia-Idade Idioma: Inglês Revista: Anticancer Res Ano de publicação: 2020 Tipo de documento: Artigo País de afiliação: Alemanha