Your browser doesn't support javascript.
loading
Chemoenzymatic Synthesis of 5-Hydroxymethylfurfural (HMF)-Derived Plasticizers by Coupling HMF Reduction with Enzymatic Esterification.
Arias, Karen S; Carceller, Jose M; Climent, Maria J; Corma, Avelino; Iborra, Sara.
Afiliação
  • Arias KS; Instituto de Tecnología Química (UPV-CSIC), Universitat Politècnica de València, Avda dels Tarongers s/n, 46022, Valencia, Spain.
  • Carceller JM; Instituto de Tecnología Química (UPV-CSIC), Universitat Politècnica de València, Avda dels Tarongers s/n, 46022, Valencia, Spain.
  • Climent MJ; Instituto de Tecnología Química (UPV-CSIC), Universitat Politècnica de València, Avda dels Tarongers s/n, 46022, Valencia, Spain.
  • Corma A; Instituto de Tecnología Química (UPV-CSIC), Universitat Politècnica de València, Avda dels Tarongers s/n, 46022, Valencia, Spain.
  • Iborra S; Instituto de Tecnología Química (UPV-CSIC), Universitat Politècnica de València, Avda dels Tarongers s/n, 46022, Valencia, Spain.
ChemSusChem ; 13(7): 1864-1875, 2020 Apr 07.
Artigo em Inglês | MEDLINE | ID: mdl-31944622
ABSTRACT
Biobased plasticizers, as substitutes for phthalates, have been synthesized from 5-hydroxymethylfurfural (HMF) and carboxylic acids (or esters) through a chemoenzymatic cascade process that involves as its first step the reduction of 5-hydroxymethylfurfural into 2,5-bis(hydroxymethyl)furan (BHMF), followed by the esterification of BHMF with carboxylic acids (or esters) by using a supported lipase (Novozym 435). The reduction of HMF into BHMF is performed by using monodisperse metallic Co nanoparticles with a thin carbon shell (Co@C) with high activity and selectivity. After optimization of reaction conditions (temperature, hydrogen pressure, and solvent), it is possible to achieve 97 % conversion of HMF with 99 % selectivity to BHMF after 2 h reaction time. The reduction of HMF and esterification of BHMF using carboxylic acids or vinyl esters as acyl donors by lipase are optimized separately in batch and in fixed-bed continuous reactors. The coupling of two flow reactors (for reduction and subsequent esterification) working under optimized reaction conditions affords the diesters of BHMF in roughly 90 % yield with no loss of activity during 60 h of operation.

Similares

MEDLINE

...
LILACS

LIS

Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Idioma: Inglês Revista: ChemSusChem Assunto da revista: Química / Toxicologia Ano de publicação: 2020 Tipo de documento: Artigo País de afiliação: Espanha