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Discovery of Balovaptan, a Vasopressin 1a Receptor Antagonist for the Treatment of Autism Spectrum Disorder.
Schnider, Patrick; Bissantz, Caterina; Bruns, Andreas; Dolente, Cosimo; Goetschi, Erwin; Jakob-Roetne, Roland; Künnecke, Basil; Mueggler, Thomas; Muster, Wolfgang; Parrott, Neil; Pinard, Emmanuel; Ratni, Hasane; Risterucci, Céline; Rogers-Evans, Mark; von Kienlin, Markus; Grundschober, Christophe.
Afiliação
  • Schnider P; Pharmaceutical Research and Early Development, Roche Innovation Center Basel , F. Hoffmann-La Roche Ltd. , Grenzacherstrasse 124 , 4070 Basel , Switzerland.
  • Bissantz C; Pharmaceutical Research and Early Development, Roche Innovation Center Basel , F. Hoffmann-La Roche Ltd. , Grenzacherstrasse 124 , 4070 Basel , Switzerland.
  • Bruns A; Pharmaceutical Research and Early Development, Roche Innovation Center Basel , F. Hoffmann-La Roche Ltd. , Grenzacherstrasse 124 , 4070 Basel , Switzerland.
  • Dolente C; Pharmaceutical Research and Early Development, Roche Innovation Center Basel , F. Hoffmann-La Roche Ltd. , Grenzacherstrasse 124 , 4070 Basel , Switzerland.
  • Goetschi E; Pharmaceutical Research and Early Development, Roche Innovation Center Basel , F. Hoffmann-La Roche Ltd. , Grenzacherstrasse 124 , 4070 Basel , Switzerland.
  • Jakob-Roetne R; Pharmaceutical Research and Early Development, Roche Innovation Center Basel , F. Hoffmann-La Roche Ltd. , Grenzacherstrasse 124 , 4070 Basel , Switzerland.
  • Künnecke B; Pharmaceutical Research and Early Development, Roche Innovation Center Basel , F. Hoffmann-La Roche Ltd. , Grenzacherstrasse 124 , 4070 Basel , Switzerland.
  • Mueggler T; Pharmaceutical Research and Early Development, Roche Innovation Center Basel , F. Hoffmann-La Roche Ltd. , Grenzacherstrasse 124 , 4070 Basel , Switzerland.
  • Muster W; Pharmaceutical Research and Early Development, Roche Innovation Center Basel , F. Hoffmann-La Roche Ltd. , Grenzacherstrasse 124 , 4070 Basel , Switzerland.
  • Parrott N; Pharmaceutical Research and Early Development, Roche Innovation Center Basel , F. Hoffmann-La Roche Ltd. , Grenzacherstrasse 124 , 4070 Basel , Switzerland.
  • Pinard E; Pharmaceutical Research and Early Development, Roche Innovation Center Basel , F. Hoffmann-La Roche Ltd. , Grenzacherstrasse 124 , 4070 Basel , Switzerland.
  • Ratni H; Pharmaceutical Research and Early Development, Roche Innovation Center Basel , F. Hoffmann-La Roche Ltd. , Grenzacherstrasse 124 , 4070 Basel , Switzerland.
  • Risterucci C; Pharmaceutical Research and Early Development, Roche Innovation Center Basel , F. Hoffmann-La Roche Ltd. , Grenzacherstrasse 124 , 4070 Basel , Switzerland.
  • Rogers-Evans M; Pharmaceutical Research and Early Development, Roche Innovation Center Basel , F. Hoffmann-La Roche Ltd. , Grenzacherstrasse 124 , 4070 Basel , Switzerland.
  • von Kienlin M; Pharmaceutical Research and Early Development, Roche Innovation Center Basel , F. Hoffmann-La Roche Ltd. , Grenzacherstrasse 124 , 4070 Basel , Switzerland.
  • Grundschober C; Pharmaceutical Research and Early Development, Roche Innovation Center Basel , F. Hoffmann-La Roche Ltd. , Grenzacherstrasse 124 , 4070 Basel , Switzerland.
J Med Chem ; 63(4): 1511-1525, 2020 02 27.
Article em En | MEDLINE | ID: mdl-31951127
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridinas / Triazóis / Benzodiazepinas / Receptores de Vasopressinas / Antagonistas dos Receptores de Hormônios Antidiuréticos / Transtorno do Espectro Autista Limite: Adolescent / Adult / Animals / Child / Female / Humans / Male Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Suíça País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridinas / Triazóis / Benzodiazepinas / Receptores de Vasopressinas / Antagonistas dos Receptores de Hormônios Antidiuréticos / Transtorno do Espectro Autista Limite: Adolescent / Adult / Animals / Child / Female / Humans / Male Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Suíça País de publicação: Estados Unidos