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Integrative analysis of genomic amplification-dependent expression and loss-of-function screen identifies ASAP1 as a driver gene in triple-negative breast cancer progression.
He, Jichao; McLaughlin, Ronan P; van der Beek, Lambert; Canisius, Sander; Wessels, Lodewyk; Smid, Marcel; Martens, John W M; Foekens, John A; Zhang, Yinghui; van de Water, Bob.
Afiliação
  • He J; Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, 2300 RA, Leiden, The Netherlands.
  • McLaughlin RP; Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, 2300 RA, Leiden, The Netherlands.
  • van der Beek L; Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, 2300 RA, Leiden, The Netherlands.
  • Canisius S; Division of Molecular Carcinogenesis, Netherlands Cancer Institute, 1066 CX, Amsterdam, The Netherlands.
  • Wessels L; Division of Molecular Carcinogenesis, Netherlands Cancer Institute, 1066 CX, Amsterdam, The Netherlands.
  • Smid M; Department of Medical Oncology and Cancer Genomic Netherlands, Erasmus MC Cancer Institute, Erasmus Medical Centre, 3000 CA, Rotterdam, The Netherlands.
  • Martens JWM; Department of Medical Oncology and Cancer Genomic Netherlands, Erasmus MC Cancer Institute, Erasmus Medical Centre, 3000 CA, Rotterdam, The Netherlands.
  • Foekens JA; Department of Medical Oncology and Cancer Genomic Netherlands, Erasmus MC Cancer Institute, Erasmus Medical Centre, 3000 CA, Rotterdam, The Netherlands.
  • Zhang Y; Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, 2300 RA, Leiden, The Netherlands.
  • van de Water B; Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, 2300 RA, Leiden, The Netherlands. b.water@lacdr.leidenuniv.nl.
Oncogene ; 39(20): 4118-4131, 2020 05.
Article em En | MEDLINE | ID: mdl-32235890

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Amplificação de Genes / Proteínas Adaptadoras de Transdução de Sinal / Neoplasias de Mama Triplo Negativas / Proteínas de Neoplasias Tipo de estudo: Prognostic_studies Limite: Female / Humans Idioma: En Revista: Oncogene Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Holanda País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Amplificação de Genes / Proteínas Adaptadoras de Transdução de Sinal / Neoplasias de Mama Triplo Negativas / Proteínas de Neoplasias Tipo de estudo: Prognostic_studies Limite: Female / Humans Idioma: En Revista: Oncogene Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Holanda País de publicação: Reino Unido