Compostos Organometálicos/farmacologia; Vanádio/farmacologia; Animais; Anti-Infecciosos/efeitos adversos; Anti-Infecciosos/farmacologia; Anticolesterolemiantes/efeitos adversos; Anticolesterolemiantes/farmacologia; Antineoplásicos/efeitos adversos; Antineoplásicos/farmacologia; Cardiotônicos/efeitos adversos; Cardiotônicos/farmacologia; Humanos; Hipoglicemiantes/efeitos adversos; Hipoglicemiantes/farmacologia; Fármacos Neuroprotetores/efeitos adversos; Fármacos Neuroprotetores/farmacologia; Compostos Organometálicos/efeitos adversos; Vanádio/efeitos adversos

3-HMG-CoA, 3-hydroxy-3-methyl-glutaryl-CoA; AIDS, acquired immune deficiency syndrome; ALB, albumin; ALP, alkaline phosphatase; AS, antioxidant status; Akt, protein kinase B (PKB); AmD, Assoc American Dietetic Association; Anti-B, anti-bacterial; Anti-C, anti-cancer; Anti-D, anti-diabetic; Anti-F, anti-fungal; Anti-O, anti-obesity; Anti-P, anti-parasitic; Anti-V, anti-viral; Anti−HC, anti-hypercholesterolemic; ApoA-I, apolipoprotein A; ApoB, apolipoprotein B; B, bone; BCOV, bis(curcumino)oxavanadyl; BEOV, bis(ethylmaltolato)oxovanadium; BMOV, bis(maltolato)oxavanadium(IV); Bim, Blc-2 interacting mediator of cell death; Biological role; BrOP, bromoperoxidase; C, cholesterol; C/EBPα, CCAAT-enhancer-binding protein α; CD4, CD4 receptor; CH, cerebral hemisphere; CHO-K1, Chinese hamster ovary cells; CXCR-4, CXCR-4 chemokine co-receptor; Cardio-P, cardioprotective; Citrate-T, citrate transporter; CoA, coenzyme A; Cyt c, cytochrome c; DM, diabetes mellitus; ELI, extra low interstitial; ERK, extracellular regulated kinase; FHR, fructose hypertensive rats; FKHR/FKHR1/AFX, class O members of the forkhead transcription factor family; FLIP, FLICE-inhibitory protein; FOXOs, forkhead box class O family member proteins; FPP, farnesyl-pyrophosphate; FasL, Fas ligand, FER: ferritin; GI, gastrointestinal; GLU, glucose; GLUT-4, glucose transporter type 4; GPP, geranyl-pyrophosphate; GPT, glutamate-pyruvate transaminase; GR, glutathione reductase; GSH, reduced glutathione; GSSG, disulfide glutathione; HDL, high-density lipoproteins; HDL-C, HDL cholesterol; HIV, human immunodeficiency virus; HMMF, high molecular mass fraction; HOMA-IR, insulin resistance index; Hb, hemoglobin; HbF, hemoglobin fraction; Hyper-LEP, hyperleptynemia; IDDM, insulin-dependent diabetes mellitus; IGF-IR, insulin-like growth factor receptor; IL, interleukin; INS, insulin; INS-R, insulin resistance; INS-S, insulin sensitivity; IPP, isopentenyl-5-pyrophosphate; IRS, insulin receptor tyrosine kinase substrate; IgG, immunoglobulin G; Industrial importance; Interactions; JAK2, Janus kinase 2; K, kidney; L, liver; L-AA, L-ascorbic acid; LDL, low-density lipoproteins; LDL-C, LDL cholesterol; LEP, leptin; LEP-R, leptin resistance; LEP-S, leptin sensitivity; LEPS, the concentration of leptin in the serum; LMMF, low molecular mass fraction; LPL, lipoprotein lipase; LPO, lipid peroxidation; Lactate-T, lactate transporter; M, mitochondrion; MEK, ERK kinase activator; MRC, mitochondrial respiratory chain; NAC, N-acetylcysteine; NEP, neutral endopeptidase; NIDDM, noninsulin-dependent diabetes mellitus; NO, nitric oxide; NPY, neuropeptide Y; NaVO3, sodium metavanadate; Neuro-P, neuroprotective; OXPHOS, oxidative phosphorylation; Organic-AT, organic anion transporter; Over-W, over-weight; P, plasma; PANC-1, pancreatic ductal adenocarcinoma cells; PARP, poly (ADP-ribose) polymerase; PLGA, (Poly)Lactide-co-Glycolide copolymer; PO43−, phosphate ion; PPARγ, peroxisome-activated receptor γ; PTK, tyrosine protein kinase; PTP, protein tyrosine phosphatase; PTP-1B, protein tyrosine phosphatase 1B; Pharmacological activity; Pi3K, phosphoinositide 3-kinase (phosphatidylinositol 3-kinase); RBC, erythrocytes; ROS, reactive oxygen species; RT, reverse transcriptase; SARS, severe acute respiratory syndrome; SAcP, acid phosphatase secreted by Leshmania; SC-Ti-6Al-4V, surface-coated Ti-6Al-4V; SHR, spontaneously hypertensive rats; SOD, superoxide dismutase; STAT3, signal transducer/activator of transcription 3; Sa, mean roughness; Sq, root mean square roughness; Sz, ten-point height; TC, total cholesterol; TG, triglycerides; TS, transferrin saturation; Tf, transferrin; TfF, transferrin fraction; TiO2, nHA:Ag-Ti-6Al-4V: titanium oxide-based coating containing hydroxyapatite nanoparticle and silver particles; Top-IB, IB type topoisomerase; Toxicological potential; V, vanadium; V-BrPO, vanadium bromoperoxidase; V-DLC, diamond-like layer with vanadium; V5+/V4+, pentavalent/tetravalent vanadium; VO2+, vanadyl cation; VO2+-FER, vanadyl-ferritin complex; VO4-/VO3-, vanadate anion; VO43-, vanadate ion; VS, vanadyl sulfate; Vanadium; WB, whole blood; ZDF rats, Zucker diabetic fatty rats; ZF rats, Zucker fatty rats; breakD, breakdown; eNOS, endothelial nitric oxide synthase; mo, months; n-HA, nano-hydroxyapatite; pRb, retinoblastoma protein; wk, weeks