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High-level mupirocin resistance in Gram-positive bacteria isolated from diseased companion animals.
Sum, Samuth; Park, Hee Myung; Oh, Jae Young.
Afiliação
  • Sum S; Department of Veterinary Internal Medicine, Konkuk University College of Veterinary Medicine, Seoul, Korea.
  • Park HM; Department of Veterinary Internal Medicine, Konkuk University College of Veterinary Medicine, Seoul, Korea.
  • Oh JY; Department of Veterinary Internal Medicine, Konkuk University College of Veterinary Medicine, Seoul, Korea. ohjy1026@gmail.com.
J Vet Sci ; 21(3): e40, 2020 May.
Artigo em Inglês | MEDLINE | ID: mdl-32476314
ABSTRACT
The purpose of this study was to investigate the high-level mupirocin resistance (HLMR) in Gram-positive bacteria isolated from companion animals. A total of 931 clinical specimens were collected from diseased pets. The detection of mupirocin-resistant bacteria and plasmid-mediated mupirocin resistance genes were evaluated by antimicrobial susceptibility tests, polymerase chain reactions, and sequencing analysis. Four-hundred and six (43.6%) bacteria were isolated and 17 (4.2%), including 14 staphylococci and 3 Corynebacterium were high-level mupirocin-resistant (MICs, ≥ 1,024 ug/mL) harboring mupA. Six staphylococci of HLMR strains had plasmid-mediated mupA-IS257 flanking regions. The results show that HLMR bacteria could spread in veterinary medicine in the near future.
Assuntos
Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Staphylococcus / Mupirocina / Corynebacterium / Farmacorresistência Bacteriana / Antibacterianos Limite: Animais Idioma: Inglês Revista: J Vet Sci Assunto da revista: Medicina Veterinária Ano de publicação: 2020 Tipo de documento: Artigo

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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Staphylococcus / Mupirocina / Corynebacterium / Farmacorresistência Bacteriana / Antibacterianos Limite: Animais Idioma: Inglês Revista: J Vet Sci Assunto da revista: Medicina Veterinária Ano de publicação: 2020 Tipo de documento: Artigo