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Dataset on the effect of Benzene exposure on genetic damage, hematotoxicity, telomere length and polymorphisms in metabolic and DNA repair genes.
Ren, Jing-Chao; Liu, Huan; Zhang, Guang-Hui; Wang, Tongshuai; Li, Jingzhi; Dong, Tingting; Wu, Hantian; Xia, Zhao-Lin.
Afiliação
  • Ren JC; School of Public Health, Xinxiang Medical University, 601 Jinsui Road, Xinxiang, 453003, China.
  • Liu H; School of Public Health, Xinxiang Medical University, 601 Jinsui Road, Xinxiang, 453003, China.
  • Zhang GH; School of Public Health, Xinxiang Medical University, 601 Jinsui Road, Xinxiang, 453003, China.
  • Wang T; Department of Occupational Health and Toxicology, School of Public Health, Fudan University, 138 Yixueyuan Road, Shanghai, 200032, China.
  • Li J; School of Public Health, Xinxiang Medical University, 601 Jinsui Road, Xinxiang, 453003, China.
  • Dong T; School of Public Health, Xinxiang Medical University, 601 Jinsui Road, Xinxiang, 453003, China.
  • Wu H; Department of Occupational Health and Toxicology, School of Public Health, Fudan University, 138 Yixueyuan Road, Shanghai, 200032, China.
  • Xia ZL; Department of Occupational Health and Toxicology, School of Public Health, Fudan University, 138 Yixueyuan Road, Shanghai, 200032, China.
Data Brief ; 31: 105869, 2020 Aug.
Article em En | MEDLINE | ID: mdl-32637486
ABSTRACT
In this paper, we present an occupational dataset to evaluate benzene exposure on the effective biomarkers of genetic damage, indicated as cytokinesis-block micronucleus (MN) frequency, hematotoxicity, indicated as white blood cells (WBC) counts, and molecular marker of telomere length (TL). And we further to eliminate the mechanism of benzene induced damage. Then evaluate the effects of sites polymorphism in environmental response genes, including 18 sites in metabolic and DNA repair genes, and the interaction between gene polymorphism and benzene exposure. This dataset is supplementary to the submitted research by [1] focused on the biomarkers TL, and a detailed description of the subjects sampling, biomarkers detection, data analysis and discussion are discussed in detail.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Data Brief Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Data Brief Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China