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Surveillance of Coronavirus Disease 2019 (COVID-19) Testing in Clinical Laboratories in Korea.
Huh, Hee Jae; Hong, Ki Ho; Kim, Taek Soo; Song, Sang Hoon; Roh, Kyoung Ho; Lee, Hyukmin; Kwon, Gye Cheol.
Afiliação
  • Huh HJ; Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
  • Hong KH; Department of Laboratory Medicine, Seoul Medical Center, Seoul, Korea.
  • Kim TS; Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea.
  • Song SH; Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea.
  • Roh KH; Department of Laboratory Medicine, National Health Insurance Service Ilsan Hospital, Goyang, Korea.
  • Lee H; Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea.
  • Kwon GC; Department of Laboratory Medicine, College of Medicine, Chungnam National University, Daejeon, Korea.
Ann Lab Med ; 41(2): 225-229, 2021 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-33063685
ABSTRACT
In response to the ongoing coronavirus disease 2019 (COVID-19) pandemic, an online laboratory surveillance system was established to monitor severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) real-time reverse transcription-PCR (rRT-PCR) testing capacities and results. SARS-CoV-2 rRT-PCR testing data were collected from 97 clinical laboratories, including 84 medical institutions and 13 independent clinical laboratories in Korea. We assessed the testing capacities to utilize SARS-CoV-2 rRT-PCR based on surveillance data obtained from February 7th to June 4th, 2020 and evaluated positive result characteristics according to the reagents used and sample types. A total of 1,890,319 SARS-CoV-2 rRT-PCR testing were performed, 2.3% of which were positive. Strong correlations were observed between the envelope (E) gene and RNA-dependent RNA polymerase (RdRp)/nucleocapsid (N) genes threshold cycle (Ct) values for each reagent. No statistically significant differences in gene Ct values were observed between the paired upper and lower respiratory tract samples, except in the N gene for nasopharyngeal swab and sputum samples. Our study showed that clinical laboratories in Korea have rapidly expanded their testing capacities in response to the COVID-19 outbreak, with a peak daily capacity of 34,193 tests. Rapid expansion in testing capacity is a critical component of the national response to the ongoing pandemic.
Assuntos
Texto completo: Disponível Coleções: Bases de dados internacionais Contexto em Saúde: ODS3 - Saúde e Bem-Estar Tema em saúde: Meta 3.4: Reduzir as mortes prematuras devido doenças não transmissíveis Base de dados: MEDLINE Assunto principal: Pneumonia Viral / Infecções por Coronavirus / Serviços de Laboratório Clínico / Betacoronavirus Tipo de estudo: Guia de prática clínica / Estudo de rastreamento Limite: Humanos País/Região como assunto: Ásia Idioma: Inglês Revista: Ann Lab Med Ano de publicação: 2021 Tipo de documento: Artigo

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Texto completo: Disponível Coleções: Bases de dados internacionais Contexto em Saúde: ODS3 - Saúde e Bem-Estar Tema em saúde: Meta 3.4: Reduzir as mortes prematuras devido doenças não transmissíveis Base de dados: MEDLINE Assunto principal: Pneumonia Viral / Infecções por Coronavirus / Serviços de Laboratório Clínico / Betacoronavirus Tipo de estudo: Guia de prática clínica / Estudo de rastreamento Limite: Humanos País/Região como assunto: Ásia Idioma: Inglês Revista: Ann Lab Med Ano de publicação: 2021 Tipo de documento: Artigo