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Accumulation of amyloid precursor protein C-terminal fragments triggers mitochondrial structure, function, and mitophagy defects in Alzheimer's disease models and human brains.
Vaillant-Beuchot, Loan; Mary, Arnaud; Pardossi-Piquard, Raphaëlle; Bourgeois, Alexandre; Lauritzen, Inger; Eysert, Fanny; Kinoshita, Paula Fernanda; Cazareth, Julie; Badot, Céline; Fragaki, Konstantina; Bussiere, Renaud; Martin, Cécile; Mary, Rosanna; Bauer, Charlotte; Pagnotta, Sophie; Paquis-Flucklinger, Véronique; Buée-Scherrer, Valérie; Buée, Luc; Lacas-Gervais, Sandra; Checler, Frédéric; Chami, Mounia.
Afiliação
  • Vaillant-Beuchot L; Institut of Molecular and Cellular Pharmacology, Laboratory of Excellence DistALZ, Université Côte d'Azur, INSERM, CNRS, Sophia-Antipolis, 06560, Valbonne, France.
  • Mary A; Institut of Molecular and Cellular Pharmacology, Laboratory of Excellence DistALZ, Université Côte d'Azur, INSERM, CNRS, Sophia-Antipolis, 06560, Valbonne, France.
  • Pardossi-Piquard R; Institut of Molecular and Cellular Pharmacology, Laboratory of Excellence DistALZ, Université Côte d'Azur, INSERM, CNRS, Sophia-Antipolis, 06560, Valbonne, France.
  • Bourgeois A; Institut of Molecular and Cellular Pharmacology, Laboratory of Excellence DistALZ, Université Côte d'Azur, INSERM, CNRS, Sophia-Antipolis, 06560, Valbonne, France.
  • Lauritzen I; Institut of Molecular and Cellular Pharmacology, Laboratory of Excellence DistALZ, Université Côte d'Azur, INSERM, CNRS, Sophia-Antipolis, 06560, Valbonne, France.
  • Eysert F; Institut of Molecular and Cellular Pharmacology, Laboratory of Excellence DistALZ, Université Côte d'Azur, INSERM, CNRS, Sophia-Antipolis, 06560, Valbonne, France.
  • Kinoshita PF; Institut of Molecular and Cellular Pharmacology, Laboratory of Excellence DistALZ, Université Côte d'Azur, INSERM, CNRS, Sophia-Antipolis, 06560, Valbonne, France.
  • Cazareth J; Department of Pharmacology, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil.
  • Badot C; Institut of Molecular and Cellular Pharmacology, Laboratory of Excellence DistALZ, Université Côte d'Azur, INSERM, CNRS, Sophia-Antipolis, 06560, Valbonne, France.
  • Fragaki K; Institut of Molecular and Cellular Pharmacology, Laboratory of Excellence DistALZ, Université Côte d'Azur, INSERM, CNRS, Sophia-Antipolis, 06560, Valbonne, France.
  • Bussiere R; Université Côte d'Azur, CHU, Inserm, CNRS, IRCAN, Nice, France.
  • Martin C; Institut of Molecular and Cellular Pharmacology, Laboratory of Excellence DistALZ, Université Côte d'Azur, INSERM, CNRS, Sophia-Antipolis, 06560, Valbonne, France.
  • Mary R; Department of Medicine, Burlington Danes Building, Hammersmith Hospital Campus, Imperial College London, UK Dementia Research Institute, Du Cane Road, London, W12 0NN, UK.
  • Bauer C; Institut of Molecular and Cellular Pharmacology, Laboratory of Excellence DistALZ, Université Côte d'Azur, INSERM, CNRS, Sophia-Antipolis, 06560, Valbonne, France.
  • Pagnotta S; Institut of Molecular and Cellular Pharmacology, Laboratory of Excellence DistALZ, Université Côte d'Azur, INSERM, CNRS, Sophia-Antipolis, 06560, Valbonne, France.
  • Paquis-Flucklinger V; Institut of Molecular and Cellular Pharmacology, Laboratory of Excellence DistALZ, Université Côte d'Azur, INSERM, CNRS, Sophia-Antipolis, 06560, Valbonne, France.
  • Buée-Scherrer V; Université Côte d'Azur, Centre Commun de Microscopie Appliquée (CCMA), Parc Valrose, 06108, Nice, France.
  • Buée L; Université Côte d'Azur, CHU, Inserm, CNRS, IRCAN, Nice, France.
  • Lacas-Gervais S; Univ. Lille, Inserm, CHU-Lille, Lille Neuroscience and Cognition, Place de Verdun, 59045, Lille, France.
  • Checler F; Inserm UMR-S 1172, Laboratory of Excellence DistALZ, 'Alzheimer and Tauopathies', Bâtiment Biserte, rue Polonovski, 59045, Lille Cedex, France.
  • Chami M; Univ. Lille, Inserm, CHU-Lille, Lille Neuroscience and Cognition, Place de Verdun, 59045, Lille, France.
Acta Neuropathol ; 141(1): 39-65, 2021 01.
Article em En | MEDLINE | ID: mdl-33079262
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Precursor de Proteína beta-Amiloide / Doença de Alzheimer / Mitofagia / Mitocôndrias Limite: Aged / Aged80 / Animals / Female / Humans Idioma: En Revista: Acta Neuropathol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: França País de publicação: Alemanha
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Precursor de Proteína beta-Amiloide / Doença de Alzheimer / Mitofagia / Mitocôndrias Limite: Aged / Aged80 / Animals / Female / Humans Idioma: En Revista: Acta Neuropathol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: França País de publicação: Alemanha