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"I feel good when I drink"-detecting childhood-onset alcohol abuse and dependence in a Ugandan community trial cohort.
Engebretsen, Ingunn Marie Stadskleiv; Nalugya, Joyce S; Skylstad, Vilde; Ndeezi, Grace; Akol, Angela; Babirye, Juliet N; Nankabirwa, Victoria; Tumwine, James K.
Afiliação
  • Engebretsen IMS; Global Mental Health Research Group, Centre for International Health, Department of Global Public Health and Primary Health Care, Faculty of Medicine, University of Bergen, Bergen, Norway.
  • Nalugya JS; Department of Psychiatry, School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.
  • Skylstad V; Global Mental Health Research Group, Centre for International Health, Department of Global Public Health and Primary Health Care, Faculty of Medicine, University of Bergen, Bergen, Norway.
  • Ndeezi G; Department of Paediatrics and Child Health, School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.
  • Akol A; Global Mental Health Research Group, Centre for International Health, Department of Global Public Health and Primary Health Care, Faculty of Medicine, University of Bergen, Bergen, Norway.
  • Babirye JN; School of Public Health, College of Health Sciences, Makerere University, Kampala, Uganda.
  • Nankabirwa V; School of Public Health, College of Health Sciences, Makerere University, Kampala, Uganda.
  • Tumwine JK; Centre for Intervention Science in Maternal and Child Health (CISMAC), Centre for International Health, Department of Global Public Health and Primary Health Care, Faculty of Medicine, University of Bergen, Bergen, Norway.
Artigo em Inglês | MEDLINE | ID: mdl-33110445
ABSTRACT

Background:

Alcohol, substance use, and mental health disorders constitute major public health issues worldwide, including in low income and lower middle-income countries, and early initiation of use is an important predictor for developing substance use disorders in later life. This study reports on the existence of childhood alcohol abuse and dependence in a sub-study of a trial cohort in Eastern Uganda.

Methods:

The project SeeTheChild-Mental Child Health in Uganda (STC) included a sub-study of the Ugandan site of the study PROMISE SB Saving Brains in Uganda and Burkina Faso. PROMISE SB was a follow-up study of a trial birth cohort (PROMISE EBF) that estimated the effect that peer counselling for exclusive breast-feeding had on the children's cognitive functioning and mental health once they reached 5-8 years of age. The STC sub-study (N = 148) used the diagnostic tool MINI-KID to assess mental health conditions in children who scored medium and high (≥ 14) on the Strengths and Difficulties Questionnaire (SDQ) in the PROMISE SB cohort N = (119/148; 80.4%). Another 29/148 (19.6%) were recruited from the PROMISE SB cohort as a comparator with low SDQ scores (< 14). Additionally, the open-ended questions in the diagnostic history were analysed. The MINI-KID comprised diagnostic questions on alcohol abuse and dependence, and descriptive data from the sub-study are presented in this paper.

Results:

A total of 11/148 (7.4%) children scored positive for alcohol abuse and dependence in this study, 10 of whom had high SDQ scores (≥ 14). The 10 children with SDQ-scores ≥ 14 had a variety of mental health comorbidities of which suicidality 3/10 (30.0%) and separation anxiety disorder 5/10 (50.0%) were the most common. The one child with an SDQ score below 14 did not have any comorbidities. Access to homemade brew, carer's knowledge of the drinking, and difficult household circumstances were issues expressed in the children's diagnostic histories.

Conclusions:

The discovery of alcohol abuse and dependence among 5-8 year olds in clinical interviews from a community based trial cohort was unexpected, and we recommend continued research and increased awareness of these conditions in this age group.Trial registration Trial registration for PROMISE SB Saving Brains in Uganda and Burkina Faso Clinicaltrials.gov (NCT01882335), 20 June 2013. Regrettably, there was a 1 month delay in the registration compared to the commenced re-inclusion in the follow-up study https//clinicaltrials.gov/ct2/show/NCT01882335?term=saving+brains&draw=2&rank=1.
Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Idioma: Inglês Revista: Child Adolesc Psychiatry Ment Health Ano de publicação: 2020 Tipo de documento: Artigo País de afiliação: Noruega

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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Idioma: Inglês Revista: Child Adolesc Psychiatry Ment Health Ano de publicação: 2020 Tipo de documento: Artigo País de afiliação: Noruega
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