Your browser doesn't support javascript.
loading
Predictors of Non-Stenting Strategy for Acute Coronary Syndrome Caused by Plaque Erosion: 4-Year Outcomes of the EROSION Study.
He, Luping; Qin, Yuhan; Xu, Yishuo; Hu, Sining; Wang, Yini; Zeng, Ming; Feng, Xue; Liu, Qi; Syed, Ikramullah; Demuyakor, Abigail; Zhao, Chen; Chen, Xi; Li, Zhaoyue; Meng, Wei; Xu, Maoen; Liu, Huimin; Ma, Lijia; Dai, Jiannan; Xing, Lei; Yu, Huai; Hou, Jingbo; Jia, Haibo; Mintz, Gary S; Yu, Bo.
Afiliação
  • He L; Department of Cardiology, The 2nd Affiliated Hospital of Harbin Medical University, Harbin, China and The Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, China.
EuroIntervention ; 2020 Nov 10.
Artigo em Inglês | MEDLINE | ID: mdl-33164894
ABSTRACT

AIMS:

To test whether a non-stenting anti-thrombotic strategy was still effective at 4-year follow-up in patients enrolled in the EROSION study and to explore potential predictors of long-term prognosis. METHODS AND

RESULTS:

Out of 55 patients who completed 1-month follow-up, 52 patients finished 4-year follow-up. The median duration was 4.8 years (4.2 - 5.8 years). The majority of patients remained free from events, and all patients were free from hard endpoints (death, myocardial infarction, stroke, bypass surgery, or heart failure). Only 1 patient had gastrointestinal bleeding, and 11 patients underwent elective target lesion revascularization (TLR). Patients in the non-TLR group had more optical coherence tomography (OCT) thrombus reduction from baseline to 1 month; 95% patients in the non-TLR group versus 45% in the TLR group (p=0.001) met the primary endpoint (thrombus volume reduction >50%). Consistent with the OCT findings, angiographic results showed that the TLR group had less improvement in diameter stenosis (p=0.014) at 1 month compared with non-TLR group.

CONCLUSIONS:

Four-year follow-up findings reconfirmed the safety of an anti-thrombotic therapy without stenting for erosion-caused acute coronary syndrome. Patients with better response to anti-thrombotic therapy in the first month were less likely to require stent implantation during the next four years.
Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Tipo de estudo: Estudo prognóstico / Fatores de risco Idioma: Inglês Assunto da revista: Angiologia / Cardiologia / Terapêutica Ano de publicação: 2020 Tipo de documento: Artigo País de afiliação: China

Similares

MEDLINE

...
LILACS

LIS

Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Tipo de estudo: Estudo prognóstico / Fatores de risco Idioma: Inglês Assunto da revista: Angiologia / Cardiologia / Terapêutica Ano de publicação: 2020 Tipo de documento: Artigo País de afiliação: China