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The dermatoscopic spectrum of cutaneous lupus erythematosus: A retrospective analysis by clinical subtype with clinicopathological correlation.
Apalla, Zoe; Papadimitriou, Ilias; Iordanidis, Dimitrios; Errichetti, Enzo; Kyrgidis, Athanassios; Rakowska, Adriana; Sotiriou, Elena; Vakirlis, Efstratios; Bakirtzi, Aikaterini; Liopyris, Konstantinos; Fotiadou, Christina; Lazaridou, Elizabeth; Lallas, Aimilios; Ioannidis, Demetrios.
Afiliação
  • Apalla Z; Second Department of Dermatology, Aristotle University of Thessaloniki, Thessaloniki, Greece.
  • Papadimitriou I; First Department of Dermatology, Aristotle University of Thessaloniki, Thessaloniki, Greece.
  • Iordanidis D; State Dermatology Department, Hippokratio General Hospital, Thessaloniki, Greece.
  • Errichetti E; Dermatology Department, University of Udine, Udine, Italy.
  • Kyrgidis A; Department of Clinical Pharmacology, Aristotle University of Thessaloniki, Thessaloniki, Greece.
  • Rakowska A; Dermatology Department, CSK MSWiA, Warsaw, Poland.
  • Sotiriou E; First Department of Dermatology, Aristotle University of Thessaloniki, Thessaloniki, Greece.
  • Vakirlis E; First Department of Dermatology, Aristotle University of Thessaloniki, Thessaloniki, Greece.
  • Bakirtzi A; First Department of Dermatology, Aristotle University of Thessaloniki, Thessaloniki, Greece.
  • Liopyris K; "Andreas Syggros" Hospital, Kapodistrian University, Athens, Greece.
  • Fotiadou C; Second Department of Dermatology, Aristotle University of Thessaloniki, Thessaloniki, Greece.
  • Lazaridou E; Second Department of Dermatology, Aristotle University of Thessaloniki, Thessaloniki, Greece.
  • Lallas A; First Department of Dermatology, Aristotle University of Thessaloniki, Thessaloniki, Greece.
  • Ioannidis D; First Department of Dermatology, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Dermatol Ther ; : e14514, 2020 Nov 09.
Artigo em Inglês | MEDLINE | ID: mdl-33166029
ABSTRACT
The skin is the most common organ of involvement during the course of lupus erythematosus (LE). The literature data concerning the dermatoscopic patterns of the different clinical variants of cutaneous LE (CLE), namely chronic (CCLE), subacute (SCLE), and acute (ACLE), are scarce. To determine the dermatoscopic spectrum of CLE and to correlate the dermatoscopic features with the histological findings. This was a retrospective, observational, multicenter, cohort study. We evaluated the dermatoscopic features in a cohort of patients diagnosed with CLE. Furthermore, we investigated their frequency per clinical subtype and correlated them with the anatomic alterations. We included 79 patients. The most prevalent dermatoscopic features of CCLE included follicular plugs (86.4%, P < .01), patchy distribution (75%, P = .1) of mostly linear curved vessels (56.8%, P = .8), white scales (68.2%, P < .01), and structureless white color (68.2%, P < .01). The most common criteria of SCLE were patchy distribution (90%, P = .1) of mostly linear curved vessels (53.3%, P = .8) and fine white scales (60%, P < .01), while ACLE was characterized by erythema (100%, P < .05) and patchy distribution (100%, P = .1) of mostly dotted vessels (60%, P = .4). Follicular plugs/rosettes in dermatoscopy strongly correlated with follicular plugs in histology (rho = 0.919). Hyperkeratosis significantly correlated with white (rho = 0.644) and yellow/brown scales (rho = 0.225), telangiectasia with linear curved vessels (rho = 0.321) and white color with dermal fibrosis (rho = 0.623). Depending on CLE subtype, distinct dermatoscopic patterns are recognized. In CLE there is a high correlation between certain dermatoscopic criteria and the underneath anatomic alteration.
Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Tipo de estudo: Estudo observacional Idioma: Inglês Revista: Dermatol Ther Assunto da revista: Dermatologia Ano de publicação: 2020 Tipo de documento: Artigo País de afiliação: Grécia

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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Tipo de estudo: Estudo observacional Idioma: Inglês Revista: Dermatol Ther Assunto da revista: Dermatologia Ano de publicação: 2020 Tipo de documento: Artigo País de afiliação: Grécia