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Progress in research into the role of abnormal glycosylation modification in tumor immunity.
Liu, Hui-Min; Ma, Le-le; Cao, Bo; Lin, Jun-Zhi; Han, Li; Li, Chun-Yu; Xu, Run-Chun; Zhang, Ding-Kun.
Afiliação
  • Liu HM; Pharmacy School, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
  • Ma LL; Pharmacy School, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
  • Cao B; Pharmacy School, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
  • Lin JZ; Central Laboratory, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610072, China.
  • Han L; Pharmacy School, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
  • Li CY; National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking UnionMedical College, Beijing, 100021, China.
  • Xu RC; Pharmacy School, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China. Electronic address: wsxrch@qq.com.
  • Zhang DK; Pharmacy School, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China; State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China. Electronic address: zhangdingkun@cdutcm.edu.c
Immunol Lett ; 229: 8-17, 2020 Nov 10.
Artigo em Inglês | MEDLINE | ID: mdl-33186635
ABSTRACT
In abnormal glycosylation, molecules of glucose or other carbohydrates in living organisms are inappropriately attached to proteins, which causes protein denaturation. Abnormal glycosylation modification is known to directly or indirectly affect the tumor escape process, but very few studies have been performed on whether protein glycosylation changes the structure and function of immune cells and immune molecules and thereby regulates the occurrence and development of tumor escape. Therefore, this article summarizes the effect of the immune system on tumor escape in association with the abnormal glycosylation process from an immunological perspective.
Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Idioma: Inglês Revista: Immunol Lett Ano de publicação: 2020 Tipo de documento: Artigo País de afiliação: China

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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Idioma: Inglês Revista: Immunol Lett Ano de publicação: 2020 Tipo de documento: Artigo País de afiliação: China