Your browser doesn't support javascript.
loading
The functions of mechanosensitive ion channels in tooth and bone tissues.
Pei, Fang; Liu, Jialing; Zhang, Lan; Pan, Xuefeng; Huang, Wei; Cen, Xiao; Huang, Shishu; Jin, Ying; Zhao, Zhihe.
Afiliação
  • Pei F; State Key Laboratory of Oral Diseases, Department of Orthodontics, West China School of Stomatology, Sichuan University, Chengdu, PR China.
  • Liu J; State Key Laboratory of Oral Diseases, Department of Orthodontics, West China School of Stomatology, Sichuan University, Chengdu, PR China.
  • Zhang L; State Key Laboratory of Oral Diseases, Department of Orthodontics, West China School of Stomatology, Sichuan University, Chengdu, PR China.
  • Pan X; State Key Laboratory of Oral Diseases, Department of Orthodontics, West China School of Stomatology, Sichuan University, Chengdu, PR China.
  • Huang W; State Key Laboratory of Oral Diseases, Department of Orthodontics, West China School of Stomatology, Sichuan University, Chengdu, PR China.
  • Cen X; Department of the Temporomandibular Joint, West China Hospital of Stomatology, Sichuan University, Chengdu,China.
  • Huang S; Department of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, China. Electronic address: h0794062@scu.edu.cn.
  • Jin Y; State Key Laboratory of Oral Diseases, Department of Orthodontics, West China School of Stomatology, Sichuan University, Chengdu, PR China. Electronic address: orthojin@163.com.
  • Zhao Z; State Key Laboratory of Oral Diseases, Department of Orthodontics, West China School of Stomatology, Sichuan University, Chengdu, PR China. Electronic address: zhzhao@scu.edu.com.
Cell Signal ; : 109877, 2020 Dec 06.
Artigo em Inglês | MEDLINE | ID: mdl-33296740
ABSTRACT
Tooth and bone are independent tissues with a close relationship. Both are composed of a highly calcified outer structure and soft inner tissue, and both are constantly under mechanical stress. In particular, the alveolar bone and tooth constitute an occlusion system and suffer from masticatory and occlusal force. Thus, mechanotransduction is a key process in many developmental, physiological and pathological processes in tooth and bone. Mechanosensitive ion channels such as Piezo1 and Piezo2 are important participants in mechanotransduction, but their functions in tooth and bone are poorly understood. This review summarizes our current understanding of mechanosensitive ion channels and their roles in tooth and bone tissues. Research in these areas may shed new light on the regulation of tooth and bone tissues and potential treatments for diseases affecting these tissues.
Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Idioma: Inglês Revista: Cell Signal Ano de publicação: 2020 Tipo de documento: Artigo

Similares

MEDLINE

...
LILACS

LIS

Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Idioma: Inglês Revista: Cell Signal Ano de publicação: 2020 Tipo de documento: Artigo
...