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Targeting oxytocin receptor (Oxtr)-expressing neurons in the lateral septum to restore social novelty in autism spectrum disorder mouse models.
Horiai, Machi; Otsuka, Ayano; Hidema, Shizu; Hiraoka, Yuichi; Hayashi, Ryotaro; Miyazaki, Shinji; Furuse, Tamio; Mizukami, Hiroaki; Teruyama, Ryoichi; Tamura, Masaru; Bito, Haruhiko; Maejima, Yuko; Shimomura, Kenju; Nishimori, Katsuhiko.
Afiliação
  • Horiai M; Department of Molecular and Cell Biology, Graduate School of Agricultural Science, Tohoku University, 468-1 Aramaki-Aza-Aoba, Aoba-ku, Sendai, Miyagi, 980-0845, Japan.
  • Otsuka A; Department of Obesity and Internal Inflammation, Fukushima Medical University, 1 Hikarigaoka, Fukushima, 960-1295, Japan.
  • Hidema S; Department of Molecular and Cell Biology, Graduate School of Agricultural Science, Tohoku University, 468-1 Aramaki-Aza-Aoba, Aoba-ku, Sendai, Miyagi, 980-0845, Japan.
  • Hiraoka Y; Department of Obesity and Internal Inflammation, Fukushima Medical University, 1 Hikarigaoka, Fukushima, 960-1295, Japan.
  • Hayashi R; Department of Bioregulation and Pharmacological Medicine, Fukushima Medical University, 1 Hikarigaoka, Fukushima, 960-1295, Japan.
  • Miyazaki S; Laboratory for Molecular Neuroscience Medical Research Institute, Tokyo Medical and Dental University, Tokyo, 113-8510, Japan.
  • Furuse T; Department of Molecular and Cell Biology, Graduate School of Agricultural Science, Tohoku University, 468-1 Aramaki-Aza-Aoba, Aoba-ku, Sendai, Miyagi, 980-0845, Japan.
  • Mizukami H; Innovation Center, Nippon Flour Mills Co., Ltd., 5-1-3 Midorigaoka, Atsugi, Kanagawa, 243-0041, Japan.
  • Teruyama R; Department of Molecular and Cell Biology, Graduate School of Agricultural Science, Tohoku University, 468-1 Aramaki-Aza-Aoba, Aoba-ku, Sendai, Miyagi, 980-0845, Japan.
  • Tamura M; Technology and Development Team for Mouse Phenotype Analysis, Japan Mouse Clinic, RIKEN BioResouce Reserch Center (BRC), 3-1-1 Koyadai, Tsukuba, Ibaraki, 305-0074, Japan.
  • Bito H; Division of Genetic Therapeutics, Center for Medicine, Jichi Medical University, Shimotsuke, Tochigi, 329-0498, Japan.
  • Maejima Y; Department of Biological Sciences, Louisiana State University, Baton Rouge, LA, 70803, USA.
  • Shimomura K; Technology and Development Team for Mouse Phenotype Analysis, Japan Mouse Clinic, RIKEN BioResouce Reserch Center (BRC), 3-1-1 Koyadai, Tsukuba, Ibaraki, 305-0074, Japan.
  • Nishimori K; Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, 113-0033, Japan.
Sci Rep ; 10(1): 22173, 2020 12 17.
Article em En | MEDLINE | ID: mdl-33335150
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Comportamento Social / Expressão Gênica / Receptores de Ocitocina / Septo do Cérebro / Transtorno do Espectro Autista / Neurônios Aspecto: Determinantes_sociais_saude Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Japão País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Comportamento Social / Expressão Gênica / Receptores de Ocitocina / Septo do Cérebro / Transtorno do Espectro Autista / Neurônios Aspecto: Determinantes_sociais_saude Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Japão País de publicação: Reino Unido