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Longitudinal analysis of subfoveal choroidal thickness after panretinal laser photocoagulation in diabetic retinopathy using swept-source optical coherence tomography.
Eleiwa, Kamel Taher; Bayoumy, Ahmed; Elhusseiny, Mahmoud Abdelrahman; Gamil, Khalid; Sharawy, Amr.
Afiliação
  • Eleiwa KT; Department of Ophthalmology, Faculty of Medicine, Benha University, Egypt.
  • Bayoumy A; Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL.
  • Elhusseiny MA; Department of Ophthalmology, Faculty of Medicine, Benha University, Egypt.
  • Gamil K; Department of Ophthalmology, Faculty of Medicine, Cairo University, Egypt.
  • Sharawy A; Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, USA.
Rom J Ophthalmol ; 64(3): 285-291, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33367162
ABSTRACT

Purpose:

To describe the central three-dimensional (3D) thickness profile of the macula (CMT) and the subfoveal choroidal region (SFCT) in diabetic retinopathy (DR) following panretinal laser photocoagulation (PRP) using swept-source optical coherence tomography (SS-OCT).

Methods:

A prospective observational study including 17 eyes with proliferative DR (PDR) and 27 eyes with severe nonproliferative DR (sNPDR)] for whom PRP was done. All subjects received SS-OCT imaging before and 3 months after PRP (POM#3). SFCT and CMT changes were analysed at both visits. Intraclass Correlation Coefficients (ICC) and Coefficients of Variation (COV) were used to test the accuracy of thickness data.

Results:

SFCT has thinned from 233 ± 54 µm before PRP treatment to 216 ± 51 µm 3 months later (p < 0.001). Likewise, CMT declined at POM#3 as compared to pre-PRP status (p<0.001). SFCT was thinner in PDR before and at POM#3 (p<0.05) than sNPDR; whereas, no significant difference was observed in CMT between both groups in the two visits. No significant changes were found between groups in SFCT and CMT at POM#3. Regarding reliability, ICCSFCT=0.98 and ICCCMT=0.99. The COVs for CMT and SFCT were 5.03% and 5.91%, respectively.

Conclusion:

The mean SFCT and CMT decreased 3 months after PRP. We also reported reliability of SFCT measurements in DR using SS-OCT. Abbreviations SS = Swept-Source, TD = time domain, SD = spectral domain, FD = Fourier-domain, 3D = three-dimensional, 2D = two-dimensional.
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Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Retina / Corioide / Fotocoagulação a Laser / Tomografia de Coerência Óptica / Retinopatia Diabética Limite: Feminino / Humanos / Masculino / Meia-Idade Idioma: Inglês Revista: Rom J Ophthalmol Ano de publicação: 2020 Tipo de documento: Artigo País de afiliação: Egito

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Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Retina / Corioide / Fotocoagulação a Laser / Tomografia de Coerência Óptica / Retinopatia Diabética Limite: Feminino / Humanos / Masculino / Meia-Idade Idioma: Inglês Revista: Rom J Ophthalmol Ano de publicação: 2020 Tipo de documento: Artigo País de afiliação: Egito
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