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Clinical characteristics and impacts of traditional Chinese medicine treatment on the convalescents of COVID-19.
An, Ya-Wen; Yuan, Bo; Wang, Jian-Chun; Wang, Cheng; Liu, Ting-Ting; Song, Shuo; Liu, Han-Qing.
Afiliação
  • An YW; Central laboratory, Shenzhen Samii Medical Center, Shenzhen, Guangdong Province, 518118, China.
  • Yuan B; Department of neurology, Shenzhen Samii Medical Center, Shenzhen, Guangdong Province, 518118, China.
  • Wang JC; Central laboratory, Shenzhen Samii Medical Center, Shenzhen, Guangdong Province, 518118, China.
  • Wang C; Department of neurology, Shenzhen Samii Medical Center, Shenzhen, Guangdong Province, 518118, China.
  • Liu TT; Department of Traditional Chinese Medicine, Shenzhen Samii Medical Center, Shenzhen, Guangdong Province, 518118, China.
  • Song S; Central laboratory, Shenzhen Samii Medical Center, Shenzhen, Guangdong Province, 518118, China.
  • Liu HQ; Central laboratory, Shenzhen Samii Medical Center, Shenzhen, Guangdong Province, 518118, China.
Int J Med Sci ; 18(3): 646-651, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33437199
ABSTRACT

Objectives:

A significant proportion of discharged COVID-19 patients still have some symptoms. Traditional Chinese medicine (TCM) has played an important role in the treatment of COVID-19, but whether it is helpful for discharged patients is still unknown. The aim of this study was to retrospectively analyze the impacts of TCM treatment on the convalescents of COVID-19.

Methods:

A total of 372 COVID-19 convalescents from February 21 to May 3 in Shenzhen, China were retrospectively analyzed, 291 of them accepted clinically examined at least once and 191 convalescents accepted TCM.

Results:

After retrospective analysis of the clinical data of convalescents accepted TCM treatment or not, we found that the white blood cell count, as well as serum interleukin-6 and procalcitonin decreased in TCM group. Serum γ-glutamyl transpeptidase was significantly decreased, while prealbumin and albumin increased in TCM group. Red blood cell, hemoglobin, and platelet count increased in TCM group. The mechanisms of TCM treatment might be the overall regulations, including balanced immune response, improved hematopoiesis and coagulation systems, enhanced functions of liver and heart, increased nutrient intake and lipid metabolism.

Conclusions:

This study suggested that TCM treatment would be beneficial for discharged COVID-19 patients. However, long-term medical observation and further study with randomized trial should be done to confirm this result. Besides, the potential molecular mechanisms of TCM treatment should be further revealed.
Assuntos
Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Medicamentos de Ervas Chinesas / Convalescença Tipo de estudo: Ensaio clínico controlado / Estudo observacional Limite: Humanos Idioma: Inglês Revista: Int J Med Sci Assunto da revista: Medicina Ano de publicação: 2021 Tipo de documento: Artigo País de afiliação: China

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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: MEDLINE Assunto principal: Medicamentos de Ervas Chinesas / Convalescença Tipo de estudo: Ensaio clínico controlado / Estudo observacional Limite: Humanos Idioma: Inglês Revista: Int J Med Sci Assunto da revista: Medicina Ano de publicação: 2021 Tipo de documento: Artigo País de afiliação: China