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The alternative serotonin transporter promoter P2 impacts gene function in females with irritable bowel syndrome.
Mohr, Sandra; Fritz, Nikola; Hammer, Christian; Martínez, Cristina; Berens, Sabrina; Schmitteckert, Stefanie; Wahl, Verena; Schmidt, Malin; Houghton, Lesley A; Goebel-Stengel, Miriam; Kabisch, Maria; Götze, Dorothea; Milovac, Irina; D'Amato, Mauro; Zheng, Tenghao; Röth, Ralph; Mönnikes, Hubert; Engel, Felicitas; Gauss, Annika; Tesarz, Jonas; Raithel, Martin; Andresen, Viola; Frieling, Thomas; Keller, Jutta; Pehl, Christian; Stein-Thöringer, Christoph; Clarke, Gerard; Kennedy, Paul J; Cryan, John F; Dinan, Timothy G; Quigley, Eamonn M M; Spiller, Robin; Beltrán, Caroll; Madrid, Ana María; Torres, Verónica; Pérez de Arce, Edith; Herzog, Wolfgang; Mayer, Emeran A; Sayuk, Gregory; Gazouli, Maria; Karamanolis, George; Kapur-Pojskic, Lejla; Bustamante, Mariona; Rabionet, Raquel; Estivil, Xavier; Franke, André; Lieb, Wolfgang; Boeckxstaens, Guy; Wouters, Mira M; Simrén, Magnus.
Afiliação
  • Mohr S; Department of Human Molecular Genetics, Institute of Human Genetics, Heidelberg University Hospital, Heidelberg, Germany.
  • Fritz N; Department of Human Molecular Genetics, Institute of Human Genetics, Heidelberg University Hospital, Heidelberg, Germany.
  • Hammer C; Department of Cancer Immunology, Genentech, South San Francisco, CA, USA.
  • Martínez C; Department of Human Genetics, Genentech, South San Francisco, CA, USA.
  • Berens S; Department of Human Molecular Genetics, Institute of Human Genetics, Heidelberg University Hospital, Heidelberg, Germany.
  • Schmitteckert S; Institut de Recerca Biomèdica de Lleida (IRBLleida), Lleida, Spain.
  • Wahl V; Lleida Institute for Biomedical Research, Dr. Pifarré Foundation (IRBLleida), Lleida, Spain.
  • Schmidt M; Department of General Internal Medicine and Psychosomatics, Heidelberg University Hospital, Heidelberg, Germany.
  • Houghton LA; Department of Human Molecular Genetics, Institute of Human Genetics, Heidelberg University Hospital, Heidelberg, Germany.
  • Goebel-Stengel M; Department of Human Molecular Genetics, Institute of Human Genetics, Heidelberg University Hospital, Heidelberg, Germany.
  • Kabisch M; Department of Human Molecular Genetics, Institute of Human Genetics, Heidelberg University Hospital, Heidelberg, Germany.
  • Götze D; Department of Translational Brain Research, Central Institute of Mental Health.
  • Milovac I; St. James's University Hospital, University of Leeds, Leeds, UK.
  • D'Amato M; Mayo Clinic, Jacksonville, FL, USA.
  • Zheng T; Department of Psychosomatic Medicine, University Hospital Tübingen, Tübingen, Germany.
  • Röth R; Department of Internal Medicine and Gastroenterology, HELIOS Clinic Rottweil, Rottweil, Germany.
  • Mönnikes H; Institute of Medical Biometry and Informatics, Heidelberg University, Heidelberg, Germany.
  • Engel F; Department of Human Molecular Genetics, Institute of Human Genetics, Heidelberg University Hospital, Heidelberg, Germany.
  • Gauss A; Faculty of Medicine, University Banja Luka, Banja Luka, Bosnia and Herzegovina.
  • Tesarz J; School of Biological Sciences, Monash University, Clayton, VIC, Australia.
  • Raithel M; Unit of Clinical Epidemiology, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.
  • Andresen V; Department of Gastrointestinal and Liver Diseases, Biodonostia HRI, San Sebastián, Spain.
  • Frieling T; IKERBASQUE, Basque Foundation for Science, Bilbao, Spain.
  • Keller J; School of Biological Sciences, Monash University, Clayton, VIC, Australia.
  • Pehl C; Unit of Clinical Epidemiology, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.
  • Stein-Thöringer C; Department of Human Molecular Genetics, Institute of Human Genetics, Heidelberg University Hospital, Heidelberg, Germany.
  • Clarke G; nCounter Core Facility, Department of Human Molecular Genetics, Heidelberg University Hospital, Heidelberg, Germany.
  • Kennedy PJ; Martin-Luther-Hospital, Berlin, Germany.
  • Cryan JF; Department of General Internal Medicine and Psychosomatics, Heidelberg University Hospital, Heidelberg, Germany.
  • Dinan TG; Department of Gastroenterology, Infectious Diseases and Intoxications, Heidelberg University, Heidelberg, Germany.
  • Quigley EMM; Department of General Internal Medicine and Psychosomatics, Heidelberg University Hospital, Heidelberg, Germany.
  • Spiller R; University of Erlangen, Erlangen, Germany.
  • Beltrán C; Israelitisches Krankenhaus, Hamburg, Germany.
  • Madrid AM; Helios Klinik Krefeld, Krefeld, Germany.
  • Torres V; Israelitisches Krankenhaus, Hamburg, Germany.
  • Pérez de Arce E; Krankenhaus Vilsbiburg, Vilsbiburg, Germany.
  • Herzog W; German Cancer Research Center, Heidelberg, Germany.
  • Mayer EA; Department of Psychiatry and Neurobehavioral Science, University College Cork, Cork, Ireland.
  • Sayuk G; APC Microbiome Ireland, University College Cork, Cork, Ireland.
  • Gazouli M; Department of Psychiatry and Neurobehavioral Science, University College Cork, Cork, Ireland.
  • Karamanolis G; APC Microbiome Ireland, University College Cork, Cork, Ireland.
  • Kapur-Pojskic L; Department of Psychiatry and Neurobehavioral Science, University College Cork, Cork, Ireland.
  • Bustamante M; APC Microbiome Ireland, University College Cork, Cork, Ireland.
  • Rabionet R; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland.
  • Estivil X; Department of Psychiatry and Neurobehavioral Science, University College Cork, Cork, Ireland.
  • Franke A; APC Microbiome Ireland, University College Cork, Cork, Ireland.
  • Lieb W; APC Microbiome Ireland, University College Cork, Cork, Ireland.
  • Boeckxstaens G; Lynda K. and David M. Underwood Center for Digestive Disorders, Houston Methodist Hospital, Weill Cornell Medical College, Houston, TX, USA.
  • Wouters MM; Nottingham Digestive Diseases Centre, University of Nottingham, Nottingham, UK.
  • Simrén M; Gastroenterology Unit, Hospital Clínico Universidad de Chile, Medicine Department, Universidad de Chile, Santiago de Chile, Chile.
J Cell Mol Med ; 25(16): 8047-8061, 2021 08.
Article em En | MEDLINE | ID: mdl-34165249
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenótipo / Biomarcadores / Serotonina / Regiões Promotoras Genéticas / Polimorfismo de Nucleotídeo Único / Síndrome do Intestino Irritável / Proteínas da Membrana Plasmática de Transporte de Serotonina Tipo de estudo: Clinical_trials / Etiology_studies Limite: Female / Humans Idioma: En Revista: J Cell Mol Med Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenótipo / Biomarcadores / Serotonina / Regiões Promotoras Genéticas / Polimorfismo de Nucleotídeo Único / Síndrome do Intestino Irritável / Proteínas da Membrana Plasmática de Transporte de Serotonina Tipo de estudo: Clinical_trials / Etiology_studies Limite: Female / Humans Idioma: En Revista: J Cell Mol Med Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Reino Unido