Risk factors associated with postoperative morbidity and mortality in D2 radical gastrectomy for gastric cancer.
Rev Gastroenterol Mex (Engl Ed)
; 87(2): 149-158, 2022.
Article
em En
| MEDLINE
| ID: mdl-34362678
ABSTRACT
INTRODUCTION AND AIMS:
Surgery is the main treatment for gastric cancer. D2 radical gastrectomy is associated with a variable postoperative morbidity and mortality rate worldwide. The aim of the present study was to identify the risk factors associated with the postoperative morbidity and mortality of D2 radical gastrectomy, with curative intent, for gastric cancer. MATERIALS ANDMETHODS:
A retrospective case series was conducted, in which the medical records were reviewed of patients with gastric cancer that underwent D2 radical gastrectomy, within the time frame of January 2014 and December 2018. Univariate and multivariate analyses were carried out to identify the risk factors related to postoperative morbidity and mortality within 90 days.RESULTS:
The percentages of postoperative morbidity and mortality in 691 patients were 23.3% and 3.3%, respectively. In the multivariate analysis, age ≥70 years (OR = 1.85, 95% CI 1.25-2.76), ASA III-IV (OR = 2.06, 95% CI 1.28-3.34), total gastrectomy (OR = 1.96, 95% CI1.19-3.23), and pancreatosplenectomy (OR = 5.41, 95% CI 1.42-20.61) were associated with greater postoperative morbidity, and age ≥70 years (OR = 4.92, 95% CI1.78-13.65), lower BMI (OR = 0.81, 95% CI 0.71-0.92), and hypoalbuminemia (OR = 0.91, 95% CI 0.85-0.98) were associated with greater mortality in distal and total D2 radical gastrectomy.CONCLUSIONS:
D2 radical gastrectomy for gastric cancer was shown to be a safe treatment, with low postoperative morbidity and mortality rates. Age ≥70 years, ASA III-IV, total gastrectomy, and pancreatosplenectomy were factors associated with a higher complication rate. Age ≥70 years, lower BMI, and hypoalbuminemia were mortality predictors in distal and total radical gastrectomy.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Gástricas
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Hipoalbuminemia
Tipo de estudo:
Etiology_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Aged
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Humans
Idioma:
En
Revista:
Rev Gastroenterol Mex (Engl Ed)
Ano de publicação:
2022
Tipo de documento:
Article
País de publicação:
MEXICO
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MX
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MÉXICO