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Discovery of a novel and selective cathepsin L inhibitor with anti-metastatic ability in vitro and in vivo against breast cancer cells.
Li, Yanchun; Ai, Xinyu; Zou, Chunyang; Liu, Yutong; Ma, Lili; Men, Jinyu; Liu, Dongyue; Sheng, Lei; Ruan, Xinhui; Liu, Haihan; Li, Weixia; Ma, Enlong; Yuan, Lei.
Afiliação
  • Li Y; Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang 110016, PR China.
  • Ai X; Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University), Ministry of Education, Shenyang 110016, PR China; Institute of Drug Research in Medicine Capital of China, Benxi 117000, PR China.
  • Zou C; Department of Pharmacy, Liaoning Vocational College of Medicine, Shenyang 110101, PR China.
  • Liu Y; Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang 110016, PR China.
  • Ma L; Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University), Ministry of Education, Shenyang 110016, PR China.
  • Men J; Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University), Ministry of Education, Shenyang 110016, PR China.
  • Liu D; Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang 110016, PR China.
  • Sheng L; Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University), Ministry of Education, Shenyang 110016, PR China; Institute of Drug Research in Medicine Capital of China, Benxi 117000, PR China.
  • Ruan X; Department of Pharmacy, Liaoning Vocational College of Medicine, Shenyang 110101, PR China.
  • Liu H; Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University), Ministry of Education, Shenyang 110016, PR China.
  • Li W; Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University), Ministry of Education, Shenyang 110016, PR China.
  • Ma E; Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang 110016, PR China.
  • Yuan L; Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University), Ministry of Education, Shenyang 110016, PR China; Institute of Drug Research in Medicine Capital of China, Benxi 117000, PR China. Electronic address: yuanlei3094@163.com.
Bioorg Chem ; 115: 105256, 2021 10.
Article em En | MEDLINE | ID: mdl-34426153
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores de Cisteína Proteinase / Descoberta de Drogas / Catepsina L / Antineoplásicos Limite: Female / Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2021 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores de Cisteína Proteinase / Descoberta de Drogas / Catepsina L / Antineoplásicos Limite: Female / Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2021 Tipo de documento: Article País de publicação: Estados Unidos