USP37 regulates DNA damage response through stabilizing and deubiquitinating BLM.

Wu, Chenming; Chang, Yiming; Chen, Junliang; Su, Yang; Li, Lei; Chen, Yuping; Li, Yunhui; Wu, Jinhuan; Huang, Jinzhou; Zhao, Fei; Wang, Wenrui; Yin, Hui; Wang, Shunli; Jin, Mingpeng; Lou, Zhenkun; Zhu, Wei-Guo; Luo, Kuntian; Zhang, Jie; Yuan, Jian

Wu, Chenming; Chang, Yiming; Chen, Junliang; Su, Yang; Li, Lei; Chen, Yuping; Li, Yunhui; Wu, Jinhuan; Huang, Jinzhou; Zhao, Fei; Wang, Wenrui; Yin, Hui; Wang, Shunli; Jin, Mingpeng; Lou, Zhenkun; Zhu, Wei-Guo; Luo, Kuntian; Zhang, Jie; Yuan, Jian.

Afiliação

Wu C; Key Laboratory of Arrhythmias of the Ministry of Education of China, Research Center for Translational Medicine, East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
Chang Y; Department of Biochemistry and Molecular Biology, Tongji University School of Medicine, Shanghai 200120, China.
Chen J; Jinzhou Medical University, Jinzhou 121001, China.
Su Y; MOE Laboratory of Biosystems Homeostasis and Protection and Innovation Center for Cell Signaling Network, Life Sciences Institute, Zhejiang University, Hangzhou 310058, China.
Li L; Key Laboratory of Arrhythmias of the Ministry of Education of China, Research Center for Translational Medicine, East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
Chen Y; Key Laboratory of Arrhythmias of the Ministry of Education of China, Research Center for Translational Medicine, East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
Li Y; Key Laboratory of Arrhythmias of the Ministry of Education of China, Research Center for Translational Medicine, East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
Wu J; Key Laboratory of Arrhythmias of the Ministry of Education of China, Research Center for Translational Medicine, East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
Huang J; Key Laboratory of Arrhythmias of the Ministry of Education of China, Research Center for Translational Medicine, East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
Zhao F; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Wang W; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Yin H; Department of Biotechnology, Bengbu Medical College, Anhui 233030, China.
Wang S; Department of Thoracic Surgery, The First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Jin M; Department of Pathology,Shanghai East Hospital, Tongji University, Shanghai 200120, China.
Lou Z; Key Laboratory of Arrhythmias of the Ministry of Education of China, Research Center for Translational Medicine, East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
Zhu WG; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Luo K; Guangdong Key Laboratory of Genome Instability and Human Disease, Shenzhen University Carson Cancer Center, Department of Biochemistry and Molecular Biology, Shenzhen University School of Medicine, Shenzhen 518060, China.
Zhang J; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Yuan J; Department of Thoracic Surgery, Shanghai Chest Hospital,Shanghai Jiao Tong University, Shanghai, China.

Nucleic Acids Res ; 49(19): 11224-11240, 2021 11 08.

Article em En | MEDLINE | ID: mdl-34606619

Assuntos

Neoplasias da Mama/genética; Reparo do DNA; Endopeptidases/genética; Regulação Neoplásica da Expressão Gênica; RecQ Helicases/genética; Animais; Proteínas Mutadas de Ataxia Telangiectasia/genética; Proteínas Mutadas de Ataxia Telangiectasia/metabolismo; Neoplasias da Mama/metabolismo; Neoplasias da Mama/mortalidade; Neoplasias da Mama/patologia; Linhagem Celular Tumoral; DNA/genética; DNA/metabolismo; Quebras de DNA de Cadeia Dupla; Replicação do DNA; Endopeptidases/metabolismo; Feminino; Células HEK293; Células HeLa; Humanos; Células MCF-7; Camundongos; Fosforilação; Ligação Proteica; Estabilidade Proteica; Proteólise; RNA Interferente Pequeno/genética; RNA Interferente Pequeno/metabolismo; RecQ Helicases/metabolismo; Análise de Sobrevida; Ubiquitinação; Ensaios Antitumorais Modelo de Xenoenxerto

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Endopeptidases / Neoplasias da Mama / Regulação Neoplásica da Expressão Gênica / Reparo do DNA / RecQ Helicases Limite: Animals / Female / Humans Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido

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