Chronic Glucocorticoids Consumption Triggers and Worsens Experimental Alzheimer's Disease-Like Pathology by Detrimental Immune Modulations.

Canet, Geoffrey; Zussy, Charleine; Hernandez, Célia; Chevallier, Nathalie; Marchi, Nicola; Desrumaux, Catherine; Givalois, Laurent

Canet, Geoffrey; Zussy, Charleine; Hernandez, Célia; Chevallier, Nathalie; Marchi, Nicola; Desrumaux, Catherine; Givalois, Laurent.

Afiliação

Canet G; Molecular Mechanisms in Neurodegenerative Dementia (MMDN) Laboratory, University of Montpellier, EPHE, INSERM, Montpellier, France.
Zussy C; Molecular Mechanisms in Neurodegenerative Dementia (MMDN) Laboratory, University of Montpellier, EPHE, INSERM, Montpellier, France.
Hernandez C; Molecular Mechanisms in Neurodegenerative Dementia (MMDN) Laboratory, University of Montpellier, EPHE, INSERM, Montpellier, France.
Chevallier N; Molecular Mechanisms in Neurodegenerative Dementia (MMDN) Laboratory, University of Montpellier, EPHE, INSERM, Montpellier, France.
Marchi N; Department of Neuroscience, Laboratory of Cerebrovascular and Glia Research, Institute of Functional Genomics, UMR CNRS-5203, INSERM-U1191, University of Montpellier, Montpellier, France.
Desrumaux C; Molecular Mechanisms in Neurodegenerative Dementia (MMDN) Laboratory, University of Montpellier, EPHE, INSERM, Montpellier, France.
Givalois L; Molecular Mechanisms in Neurodegenerative Dementia (MMDN) Laboratory, University of Montpellier, EPHE, INSERM, Montpellier, France.

Neuroendocrinology ; 112(10): 982-997, 2022.

Article em En | MEDLINE | ID: mdl-34923495

Assuntos

Doença de Alzheimer; Água Potável; Doença de Alzheimer/metabolismo; Animais; Corticosterona; Modelos Animais de Doenças; Glucocorticoides/metabolismo; Glucocorticoides/toxicidade; Hipocampo/metabolismo; Camundongos; Camundongos Transgênicos; Ratos; Receptores de Glucocorticoides/metabolismo; Proteínas tau/metabolismo

Palavras-chave

Alzheimer's disease; Amyloid toxicity; Chronic glucocorticoids consumption; Memory deficits; Neuroinflammation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Água Potável / Doença de Alzheimer Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: Neuroendocrinology Ano de publicação: 2022 Tipo de documento: Article País de afiliação: França País de publicação: Suíça

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