Your browser doesn't support javascript.
loading
A novel aryl-guanidinium derivative, VP79s, targets the signal transducer and activator of transcription 3 signaling pathway, downregulates myeloid cell leukaemia-1 and exhibits preclinical activity against multiple myeloma.
Amet, Rebecca; Previtali, Viola; Mihigo, Helene B; Sheridan, Emily; Brophy, Sarah; Hante, Nadhim Kamil; Santos-Martinez, Maria Jose; Hayden, Patrick J; Browne, Paul V; Rozas, Isabel; McElligott, Anthony M; Zisterer, Daniela M.
Afiliação
  • Amet R; School of Biochemistry and Immunology, Trinity College Dublin, Dublin 2, Ireland; John Durkan Leukaemia Laboratories, Trinity Translational Medicine Institute, Trinity College Dublin, Dublin 8, Ireland.
  • Previtali V; School of Chemistry, Trinity College Dublin, Dublin 2, Ireland.
  • Mihigo HB; School of Chemistry, Trinity College Dublin, Dublin 2, Ireland.
  • Sheridan E; School of Biochemistry and Immunology, Trinity College Dublin, Dublin 2, Ireland.
  • Brophy S; John Durkan Leukaemia Laboratories, Trinity Translational Medicine Institute, Trinity College Dublin, Dublin 8, Ireland.
  • Hante NK; School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Dublin 2, Ireland.
  • Santos-Martinez MJ; School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Dublin 2, Ireland; School of Medicine, Trinity College Dublin, Dublin 2, Ireland.
  • Hayden PJ; Department of Haematology, St. James's Hospital, Dublin 8, Ireland; Trinity St. James's Cancer Institute, Trinity College and St James's Hospital, Dublin 8, Ireland.
  • Browne PV; Department of Haematology, St. James's Hospital, Dublin 8, Ireland; Trinity St. James's Cancer Institute, Trinity College and St James's Hospital, Dublin 8, Ireland.
  • Rozas I; School of Chemistry, Trinity College Dublin, Dublin 2, Ireland.
  • McElligott AM; John Durkan Leukaemia Laboratories, Trinity Translational Medicine Institute, Trinity College Dublin, Dublin 8, Ireland; Trinity St. James's Cancer Institute, Trinity College and St James's Hospital, Dublin 8, Ireland. Electronic address: tony.mcelligott@tcd.ie.
  • Zisterer DM; School of Biochemistry and Immunology, Trinity College Dublin, Dublin 2, Ireland.
Life Sci ; 290: 120236, 2022 Feb 01.
Article em En | MEDLINE | ID: mdl-34953891
Assuntos
Palavras-chave
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Guanidina / Fator de Transcrição STAT3 / Mieloma Múltiplo Limite: Humans Idioma: En Revista: Life Sci Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Irlanda País de publicação: Holanda
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Guanidina / Fator de Transcrição STAT3 / Mieloma Múltiplo Limite: Humans Idioma: En Revista: Life Sci Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Irlanda País de publicação: Holanda