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Sox2 induces glioblastoma cell stemness and tumor propagation by repressing TET2 and deregulating 5hmC and 5mC DNA modifications.
Lopez-Bertoni, Hernando; Johnson, Amanda; Rui, Yuan; Lal, Bachchu; Sall, Sophie; Malloy, Maureen; Coulter, Jonathan B; Lugo-Fagundo, Maria; Shudir, Sweta; Khela, Harmon; Caputo, Christopher; Green, Jordan J; Laterra, John.
Afiliação
  • Lopez-Bertoni H; Hugo W. Moser Research Institute at Kennedy Krieger, Baltimore, MD, USA. Lopezbertoni@kennedykrieger.org.
  • Johnson A; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Lopezbertoni@kennedykrieger.org.
  • Rui Y; Hugo W. Moser Research Institute at Kennedy Krieger, Baltimore, MD, USA.
  • Lal B; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Sall S; Department of Biomedical Engineering, Institute for NanoBioTechnology, and the Translational Tissue Engineering Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Malloy M; Hugo W. Moser Research Institute at Kennedy Krieger, Baltimore, MD, USA.
  • Coulter JB; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Lugo-Fagundo M; Hugo W. Moser Research Institute at Kennedy Krieger, Baltimore, MD, USA.
  • Shudir S; Bloomberg School of Public Health, Department of Environmental Health and Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Khela H; Bloomberg School of Public Health, Department of Environmental Health and Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Caputo C; The Department of Radiation Oncology and Molecular Radiation Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Green JJ; Hugo W. Moser Research Institute at Kennedy Krieger, Baltimore, MD, USA.
  • Laterra J; Hugo W. Moser Research Institute at Kennedy Krieger, Baltimore, MD, USA.
Signal Transduct Target Ther ; 7(1): 37, 2022 02 09.
Article em En | MEDLINE | ID: mdl-35136034
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Neoplasias Encefálicas / DNA de Neoplasias / Glioblastoma / Metilação de DNA / Dioxigenases / Proteínas de Ligação a DNA / Fatores de Transcrição SOXB1 / Proteínas de Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Signal Transduct Target Ther Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Neoplasias Encefálicas / DNA de Neoplasias / Glioblastoma / Metilação de DNA / Dioxigenases / Proteínas de Ligação a DNA / Fatores de Transcrição SOXB1 / Proteínas de Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Signal Transduct Target Ther Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido