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In vivo prime editing of a metabolic liver disease in mice.
Böck, Desirée; Rothgangl, Tanja; Villiger, Lukas; Schmidheini, Lukas; Matsushita, Mai; Mathis, Nicolas; Ioannidi, Eleonora; Rimann, Nicole; Grisch-Chan, Hiu Man; Kreutzer, Susanne; Kontarakis, Zacharias; Kopf, Manfred; Thöny, Beat; Schwank, Gerald.
Afiliação
  • Böck D; Institute of Pharmacology and Toxicology, University of Zurich, 8057 Zürich, Switzerland.
  • Rothgangl T; Institute of Pharmacology and Toxicology, University of Zurich, 8057 Zürich, Switzerland.
  • Villiger L; Institute of Pharmacology and Toxicology, University of Zurich, 8057 Zürich, Switzerland.
  • Schmidheini L; Institute of Pharmacology and Toxicology, University of Zurich, 8057 Zürich, Switzerland.
  • Matsushita M; Institute of Molecular Health Sciences, ETH Zürich, 8093 Zürich, Switzerland.
  • Mathis N; Institute of Molecular Health Sciences, ETH Zürich, 8093 Zürich, Switzerland.
  • Ioannidi E; Institute of Pharmacology and Toxicology, University of Zurich, 8057 Zürich, Switzerland.
  • Rimann N; Institute of Pharmacology and Toxicology, University of Zurich, 8057 Zürich, Switzerland.
  • Grisch-Chan HM; Division of Metabolism and Children's Research Center, University Children's Hospital Zurich, 8032 Zürich, Switzerland.
  • Kreutzer S; Division of Metabolism and Children's Research Center, University Children's Hospital Zurich, 8032 Zürich, Switzerland.
  • Kontarakis Z; Genome Engineering and Measurement Laboratory (GEML), ETH Zürich, 8093 Zürich, Switzerland.
  • Kopf M; Functional Genomics Center Zurich, ETH Zürich/University of Zurich, 8057 Zürich, Switzerland.
  • Thöny B; Genome Engineering and Measurement Laboratory (GEML), ETH Zürich, 8093 Zürich, Switzerland.
  • Schwank G; Functional Genomics Center Zurich, ETH Zürich/University of Zurich, 8057 Zürich, Switzerland.
Sci Transl Med ; 14(636): eabl9238, 2022 03 16.
Article em En | MEDLINE | ID: mdl-35294257

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenilcetonúrias / Hepatopatias Limite: Animals Idioma: En Revista: Sci Transl Med Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Suíça País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenilcetonúrias / Hepatopatias Limite: Animals Idioma: En Revista: Sci Transl Med Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Suíça País de publicação: Estados Unidos