Specific Interaction of DARPin with HIV-1 CA<sub>NTD</sub> Disturbs the Distribution of Gag, RNA Packaging, and Tetraspanin Remodelling in the Membrane.

Moonmuang, Sutpirat; Maniratanachote, Rawiwan; Chetprayoon, Paninee; Sornsuwan, Kanokporn; Thongkum, Weeraya; Chupradit, Koollawat; Tayapiwatana, Chatchai

Specific Interaction of DARPin with HIV-1 CA_NTD Disturbs the Distribution of Gag, RNA Packaging, and Tetraspanin Remodelling in the Membrane.

Moonmuang, Sutpirat; Maniratanachote, Rawiwan; Chetprayoon, Paninee; Sornsuwan, Kanokporn; Thongkum, Weeraya; Chupradit, Koollawat; Tayapiwatana, Chatchai.

Afiliação

Moonmuang S; Center of Biomolecular Therapy and Diagnostic, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.
Maniratanachote R; Department of Medical Technology, Division of Clinical Immunology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.
Chetprayoon P; Toxicology and Bio Evaluation Service Center (TBES), National Science and Technology Development Agency (NSTDA), Pathum Thani 12120, Thailand.
Sornsuwan K; Toxicology and Bio Evaluation Service Center (TBES), National Science and Technology Development Agency (NSTDA), Pathum Thani 12120, Thailand.
Thongkum W; Center of Biomolecular Therapy and Diagnostic, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.
Chupradit K; Center of Biomolecular Therapy and Diagnostic, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.
Tayapiwatana C; Center of Innovative Immunodiagnostic Development, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.

Viruses ; 14(4)2022 04 15.

Article em En | MEDLINE | ID: mdl-35458554

Assuntos

Proteínas de Repetição de Anquirina Projetadas; HIV-1; Antivirais/farmacologia; Capsídeo/metabolismo; Proteínas do Capsídeo/genética; HIV-1/genética; HIV-1/metabolismo; Humanos; RNA; RNA Viral/metabolismo; Tetraspaninas; Montagem de Vírus; Produtos do Gene gag do Vírus da Imunodeficiência Humana/genética; Produtos do Gene gag do Vírus da Imunodeficiência Humana/metabolismo

Palavras-chave

Gag polyprotein; HIV-1; ankyrin; tetraspanin; virus assembly inhibitor

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: HIV-1 / Proteínas de Repetição de Anquirina Projetadas Limite: Humans Idioma: En Revista: Viruses Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Tailândia País de publicação: Suíça

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