Body mass index, breast density, and the risk of breast cancer development in relation to the menopausal status; results from a population-based screening program in a native African-Arab country.
Acta Radiol Open
; 11(6): 20584601221111704, 2022 Jun.
Article
em En
| MEDLINE
| ID: mdl-35795247
ABSTRACT
Background:
Risk factors are traits or behaviors that have an influence on the development of breast cancer (BC). Awareness of the prevalent risk factors can guide in developing prevention interventions.Purpose:
To evaluate the correlation between the breast density, body mass index, and the risk of breast cancer development in relation to the menopausal status in a native African-Arab population. Material andmethods:
The study included 30,443 screened females who were classified into cancer and non-cancer groups and each group was further sub-classified into pre- and postmenopausal groups. The breast density (BD) was reported and subjectively classified according to the 2013 ACR BI-RADS breast density classification. The weight and height were measured, and the body mass index (BMI) was calculated and classified according to the WHO BMI classification.Results:
A statistically significant difference was calculated between the mean BMI in the cancer and non-cancer groups (p .027) as well as between the pre- and postmenopausal groups (p < .001). A positive statistically insignificant correlation was calculated between the breast density and the risk of breast cancer in the premenopausal group (OR 1.062, p .919) and a negative highly significant correlation was calculated in the postmenopausal group (OR 0.234, p < .001).Conclusion:
BMI and BD are inversely associated with each other. The current studied population presented unique ethnic characteristics, where a decreased BD and an increased BMI were found to be independent risk factors for developing breast cancer.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Risk_factors_studies
/
Screening_studies
Idioma:
En
Revista:
Acta Radiol Open
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Egito