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A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids.
Ramdas, Shweta; Judd, Jonathan; Graham, Sarah E; Kanoni, Stavroula; Wang, Yuxuan; Surakka, Ida; Wenz, Brandon; Clarke, Shoa L; Chesi, Alessandra; Wells, Andrew; Bhatti, Konain Fatima; Vedantam, Sailaja; Winkler, Thomas W; Locke, Adam E; Marouli, Eirini; Zajac, Greg J M; Wu, Kuan-Han H; Ntalla, Ioanna; Hui, Qin; Klarin, Derek; Hilliard, Austin T; Wang, Zeyuan; Xue, Chao; Thorleifsson, Gudmar; Helgadottir, Anna; Gudbjartsson, Daniel F; Holm, Hilma; Olafsson, Isleifur; Hwang, Mi Yeong; Han, Sohee; Akiyama, Masato; Sakaue, Saori; Terao, Chikashi; Kanai, Masahiro; Zhou, Wei; Brumpton, Ben M; Rasheed, Humaira; Havulinna, Aki S; Veturi, Yogasudha; Pacheco, Jennifer Allen; Rosenthal, Elisabeth A; Lingren, Todd; Feng, QiPing; Kullo, Iftikhar J; Narita, Akira; Takayama, Jun; Martin, Hilary C; Hunt, Karen A; Trivedi, Bhavi; Haessler, Jeffrey.
Afiliação
  • Ramdas S; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Judd J; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA.
  • Graham SE; Department of Internal Medicine, Division of Cardiology, University of Michigan, Ann Arbor, MI 48109, USA.
  • Kanoni S; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London EC1M 6BQ, UK.
  • Wang Y; Department of Biostatistics, Boston University School of Public Health, 801 Massachusetts Avenue, Boston, MA 02118, USA.
  • Surakka I; Department of Internal Medicine, Division of Cardiology, University of Michigan, Ann Arbor, MI 48109, USA.
  • Wenz B; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Clarke SL; VA Palo Alto Health Care Systems, Palo Alto, CA, USA; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
  • Chesi A; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Wells A; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Bhatti KF; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London EC1M 6BQ, UK.
  • Vedantam S; Endocrinology, Boston Childrens Hospital, Boston, MA 02115, USA; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, 75 Ames street, Cambridge, MA 02142, USA.
  • Winkler TW; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.
  • Locke AE; McDonnell Genome Institute and Department of Medicine, Washington University, St. Louis, MO 63108, USA.
  • Marouli E; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London EC1M 6BQ, UK.
  • Zajac GJM; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.
  • Wu KH; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
  • Ntalla I; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, EC1M 6BQ London, UK.
  • Hui Q; Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, GA, USA; Atlanta VA Health Care System, Decatur, GA, USA.
  • Klarin D; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, 75 Ames street, Cambridge, MA 02142, USA; Malcolm Randall VA Medical Center, Gainesville, FL, USA; Division of Vascular Surgery and Endovascular Therapy, University of Florida College of Medicine, Gainesville, FL, USA.
  • Hilliard AT; VA Palo Alto Health Care Systems, Palo Alto, CA, USA.
  • Wang Z; Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, GA, USA; Atlanta VA Health Care System, Decatur, GA, USA.
  • Xue C; Department of Internal Medicine, Division of Cardiology, University of Michigan, Ann Arbor, MI 48109, USA.
  • Thorleifsson G; deCODE genetics/Amgen, Inc., Sturlugata 8, Reykjavik 102, Iceland.
  • Helgadottir A; deCODE genetics/Amgen, Inc., Sturlugata 8, Reykjavik 102, Iceland.
  • Gudbjartsson DF; deCODE genetics/Amgen, Inc., Sturlugata 8, Reykjavik 102, Iceland; School of Engineering and Natural Sciences, University of Iceland, Sæmundargötu 2, Reykjavik 102, Iceland.
  • Holm H; deCODE genetics/Amgen, Inc., Sturlugata 8, Reykjavik 102, Iceland.
  • Olafsson I; Department of Clinical Biochemistry, Landspitali - National University Hospital of Iceland, Hringbraut, Reykjavik 101, Iceland.
  • Hwang MY; Division of Genome Science, Department of Precision Medicine, National Institute of Health, Chungbuk, South Korea.
  • Han S; Division of Genome Science, Department of Precision Medicine, National Institute of Health, Chungbuk, South Korea.
  • Akiyama M; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan; Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
  • Sakaue S; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Osaka, Japan; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, The University of Tokyo, Tokyo, Japan; Department of Allergy and Rheumatology, Graduate School of Medicine, The Universi
  • Terao C; Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
  • Kanai M; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, 75 Ames street, Cambridge, MA 02142, USA; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA
  • Zhou W; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, 75 Ames street, Cambridge, MA 02142, USA; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Bos
  • Brumpton BM; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway; MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, BS8 2BN Bristol, UK;
  • Rasheed H; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway; MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, BS8 2BN Bristol, UK;
  • Havulinna AS; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Tukholmankatu 8, 00014 Helsinki, Finland; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland.
  • Veturi Y; Department of Genetics, Institute for Biomedical Informatics, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA 19104, USA.
  • Pacheco JA; Center for Genetic Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Rosenthal EA; Department of Medicine (Medical Genetics), University of Washington, Seattle, WA, USA.
  • Lingren T; Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Feng Q; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Kullo IJ; Department of Cardiovascular Medicine and the Gonda Vascular Center, Mayo Clinic, Rochester, MN, USA.
  • Narita A; Tohoku Medical Megabank Organization, Tohoku University, Sendai 980-8573, Japan.
  • Takayama J; Tohoku Medical Megabank Organization, Tohoku University, Sendai 980-8573, Japan.
  • Martin HC; Wellcome Trust Sanger Institute, CB10 1SA Hinxton, UK.
  • Hunt KA; Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  • Trivedi B; Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  • Haessler J; Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Seattle, WA 98109, USA.
Am J Hum Genet ; 109(8): 1366-1387, 2022 08 04.
Article em En | MEDLINE | ID: mdl-35931049
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polimorfismo de Nucleotídeo Único / Estudo de Associação Genômica Ampla Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Am J Hum Genet Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polimorfismo de Nucleotídeo Único / Estudo de Associação Genômica Ampla Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Am J Hum Genet Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos