Metformin suppresses calcium oxalate crystal-induced kidney injury by promoting Sirt1 and M2 macrophage-mediated anti-inflammatory activation.

Liu, Haoran; Duan, Chen; Yang, Xiaoqi; Liu, Jianhe; Deng, Yaoliang; Tiselius, Hans-Göran; Ye, Zhangqun; Wang, Tao; Xing, Jinchun; Xu, Hua

Liu, Haoran; Duan, Chen; Yang, Xiaoqi; Liu, Jianhe; Deng, Yaoliang; Tiselius, Hans-Göran; Ye, Zhangqun; Wang, Tao; Xing, Jinchun; Xu, Hua.

Afiliação

Liu H; Department of Urology, The First Affiliated Hospital of Anhui Medical University, 230000, Hefei, China.
Duan C; Bio-X, Stanford University, 94303, Stanford, California, USA.
Yang X; Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430000, Wuhan, China.
Liu J; Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430000, Wuhan, China.
Deng Y; Department of Urology, The Second Affiliated Hospital of Kunming Medical University, 650000, Kunming, China.
Tiselius HG; Department of Urology, The First Affiliated Hospital of Guangxi Medical University, 530000, Nanning, China.
Ye Z; Division of Urology, Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet, 13820, Stockholm, Sweden.
Wang T; Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430000, Wuhan, China.
Xing J; Department of Urology, The First Affiliated Hospital of Xiamen University, 361000, Xiamen, China.
Xu H; Department of Urology, The First Affiliated Hospital of Xiamen University, 361000, Xiamen, China.

Signal Transduct Target Ther ; 8(1): 38, 2023 01 27.

Article em En | MEDLINE | ID: mdl-36702833

Assuntos

Oxalato de Cálcio; Metformina; Metformina/farmacologia; Sirtuína 1/genética; Rim; Macrófagos; Anti-Inflamatórios/farmacologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxalato de Cálcio / Metformina Idioma: En Revista: Signal Transduct Target Ther Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido

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