A single-cell atlas reveals the heterogeneity of meningeal immunity in a mouse model of Methyl CpG binding protein 2 deficiency.

Li, Huiping; Hu, Meixin; Huang, Zhuxi; Wang, Yi; Xu, Ying; Deng, Jingxin; Zhu, Ming; Feng, Weijun; Xu, Xiu

Li, Huiping; Hu, Meixin; Huang, Zhuxi; Wang, Yi; Xu, Ying; Deng, Jingxin; Zhu, Ming; Feng, Weijun; Xu, Xiu.

Afiliação

Li H; Department of Child Health Care, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.
Hu M; Department of Child Health Care, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.
Huang Z; Institute of Pediatrics, Children's Hospital of Fudan University, Shanghai, China.
Wang Y; Shanghai Key Laboratory of Medical Epigenetics, International Co-laboratory of Medical Epigenetics and Metabolism, Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai, China.
Xu Y; Department of Child Health Care, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.
Deng J; Institute of Pediatrics, Children's Hospital of Fudan University, Shanghai, China.
Zhu M; Shanghai Key Laboratory of Medical Epigenetics, International Co-laboratory of Medical Epigenetics and Metabolism, Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai, China.
Feng W; Department of Child Health Care, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.
Xu X; Institute of Pediatrics, Children's Hospital of Fudan University, Shanghai, China.

Front Immunol ; 13: 1056447, 2022.

Article em En | MEDLINE | ID: mdl-36703978

Assuntos

Proteína 2 de Ligação a Metil-CpG; Síndrome de Rett; Animais; Camundongos; Linfócitos T CD8-Positivos/metabolismo; Meninges/metabolismo; Proteína 2 de Ligação a Metil-CpG/genética; Proteína 2 de Ligação a Metil-CpG/metabolismo; Camundongos Knockout; Síndrome de Rett/genética; Síndrome de Rett/metabolismo

Palavras-chave

Rett syndrome; central nervous system; meningeal immunity; methyl CpG binding protein 2; mouse model; single-cell analysis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndrome de Rett / Proteína 2 de Ligação a Metil-CpG Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Front Immunol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China País de publicação: Suíça

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