Structural features stabilized by divalent cation coordination within hepatitis E virus ORF1 are critical for viral replication.

LeDesma, Robert; Heller, Brigitte; Biswas, Abhishek; Maya, Stephanie; Gili, Stefania; Higgins, John; Ploss, Alexander

LeDesma, Robert; Heller, Brigitte; Biswas, Abhishek; Maya, Stephanie; Gili, Stefania; Higgins, John; Ploss, Alexander.

Afiliação

LeDesma R; Department of Molecular Biology, Lewis Thomas Laboratory, Princeton University, Princeton, United States.
Heller B; Department of Molecular Biology, Lewis Thomas Laboratory, Princeton University, Princeton, United States.
Biswas A; Department of Molecular Biology, Lewis Thomas Laboratory, Princeton University, Princeton, United States.
Maya S; Department of Molecular Biology, Lewis Thomas Laboratory, Princeton University, Princeton, United States.
Gili S; Department of Geosciences, Princeton University, Princeton, United States.
Higgins J; Department of Geosciences, Princeton University, Princeton, United States.
Ploss A; Department of Molecular Biology, Lewis Thomas Laboratory, Princeton University, Princeton, United States.

Elife ; 122023 02 28.

Article em En | MEDLINE | ID: mdl-36852909

Assuntos

Vírus da Hepatite E; Calpaína; Cátions Bivalentes; Cisteína; Vírus da Hepatite E/genética; Replicação Viral; Proteínas Virais/genética

Palavras-chave

hepatitis E virus; infectious disease; microbiology; molecular biophysics; replication; structural biology; viral hepatitis; virus infection; viruses

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus da Hepatite E Idioma: En Revista: Elife Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido

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